Staff
Cardiology
Clinical Care Research
Clinical Decision Making, Informatics and Telemedicine
Clinical Nutrition
Endocrinology
Gastroenterology
General Medicine
Geographic Medicine and Infectious Diseases
Hematology-Oncology
Nephrology
Pulmonary, Critical Care and Sleep
Rheumatology
Deeb N. Salem, MD, Physician-in-Chief
Michael Barza, MD, Vice Chairman
Linden Hu, MD, Vice Chairman
Rickard Karas, MD, Vice Chairman
Richard I. Kopelman, MD, Vice Chairman
Director, Medical House Staff Training Program
Carolyn D'Ambrosio, Associate Program Director
Joseph Rencic, MD, Associate program Director
Jerome Kassirer, MD, Senior Physician
Jason Kinzel, MD, Chief Resident
Kimberly Schelling, Chief Resident
Cynthia Yan, MD, Chief Resident
Marvin Konstam, MD, Chief
Robert Blaustein, MD
Patrick Blomberg, MD
Lawrence Conway, MD
Gregory Corrodi, MD
David DeNofrio, MD
N.A. Mark Estes, III, MD
Caroline Foote, MD
Solomon Gabbay, MD
Jonas Galper, MD
Ann Garlitski, MD
Munther Homoud, MD
Gordon Huggins, MD
Navin Kapur, MD
Richard Karas, MD, PhD
Carey Kimmelstiel, MD
Rajan Krishnamani, MD
Jeffrey Kuvin, MD
Herbert Levine, MD
Mark Link, MD
Anthony Marks, MD
Michael Mendelsohn, MD
Shapur Naimi, MD
Teresa Palabrica, MD
Natesa Pandian, MD
Ayan Patel, MD
Richard Patten, MD
Stephen Pauker, MD
Gregory Russell, MD
Deeb Salem, MD
Gordon Saperia, MD
Howard Surks, MD
James Udelson, MD
David Venesey, MD
Dana Washburn, MD
Jonathan Weinstock, MD
Andrew Weintraub, MD
The Cardiology Division is widely respected for the breadth and quality of both its academic accomplishment and its clinical service. It offers extensive opportunities in every aspect of cardiovascular research.
The clinical service is strongly linked to a wide network of community-based clinicians and represents a major referral site for all forms of cardiovascular disease. The clinical material is exceptional.
The Interventional Cardiology Service conducts cutting-edge research in areas of anti-thrombotic treatment, recombinant therapies directed at vascular growth, novel interventional devices and intra-pericardial drug delivery. The service performs a full array of diagnostic and therapeutic interventions.
The New England Cardiac Arrhythmia Center is nationally respected in all areas of arrhythmia management. Its interests include radiofrequency and microwave ablation of ventricular and supraventricular arrhythmias, implantation of cardiac defibrillators and pacemakers, evaluation of patients with syncope and advanced management of atrial fibrillation. The group has a major interest in defining the indications for implantable defibrillators.
The Heart Failure and Cardiac Transplant Center is one of the premier programs of its kind. It has an extensive record of investigating novel pharmacological interventions, with particular attention to the influence on hemodynamics, ventricular remodeling and survival. The center conducts a broad range of research activities, ranging from investigation of transgenic strains in a mouse model of myocardial infarction to a demonstration project in disease management for heart failure.
The Noninvasive Laboratory has provided major advances in the non-invasive assessment of myocardial, valvular, congenital and ischemic heart disease. The research focus has been three-dimensional cardiac imaging, myocardial perfusion imaging, and ventricular shape analysis
The Nuclear Cardiology Laboratory provides extensive testing of myocardial perfusion, inducible ischemia and systolic and diastolic function. Its research is focused on myocardial viability, myocardial remodeling and the development of novel radionuclide diagnostic techniques. Its staff direct a major nationwide study of the effectiveness of radionuclide diagnosis of myocardial ischemia in the emergency room.
The Preventive Cardiology Center represents a major regional referral site for patients at high risk for the development or recurrence of cardiovascular morbid events. Research is conducted in the development of novel lipid lowering agents and into the pathophysiology and treatment of endothelial dysfunction.
The Molecular Cardiology Research Institute has achieved nationwide recognition for its wide variety of investigation into the molecular mechanisms of cardiovascular function and disease.
Harry Selker, MD, MSPH, Chief
Ethan Balk, MD
Patricia Hibberd, MD
David Kent, MD
Joseph Lau, MD
Ira Wilson, MD
The Division of Clinical Care Research studies the factors that affect clinical care and its outcomes, including the very development of research methods for such studies. The wide range of research in the Division includes development and testing of clinical treatment strategies, health policy, health and functional outcomes measurements tools, clinical decision aids, and computer-based systems aimed at improving care. The Division includes an array of component programs. Its Center for Cardiovascular Health Services Research has a focus on emergency and cardiac care. The Division's Center for Clinical Evidence Synthesis, its U.S. Cochrane Center, one of two in the nation and its Federal Agency for Healthcare Research and Quality-sponsored Evidence-based Practice Center (EPC) have ongoing programs in meta-analysis, compilation of clinical study data, creation of evidence-based medicine reports and development of new analytic methods. The Biostatistics Research Center (BRC) provides statistical consultation and support to investigators and has programs in the development of biostatistical analytic methods, and mathematical models for predicting clinical outcomes. Also within the Division, The Health Institute studies the measurement of health function and clinical outcomes as they relate to clinical care, work place environment, and health care policy.
In addition to its research programs, the Division has a campus-wide clinical research training role. It teaches a wide variety of courses and seminars in clinical research methods, biostatistics, data management, and scientific writing and data presentation. Post-doctoral fellowship training is available in health services and clinical care research.
John Wong, MD, Chief
Stephen Pauker, MD
The CDM Division has been a pioneer in the applications of decision analysis to making choices in clinical medicine. The division attempts to identify strategies that lead to optimal patient care, e.g., minimizing unnecessary test, drugs, and procedures, increasing patient participation, and decreasing the cost of medical care. The Division provides research opportunities for house staff to pursue clinical projects in their areas of interest. Such projects can tackle clinical research questions about 1) the thorough and efficient evaluation of diagnostic possibilities, 2) the value or information content of the medical history, physical examination and diagnostic tests, 3) determination of the optimal diagnostic test or test sequence, 4) selection of the optimal therapy, and 5) evaluation of new medical technologies (tests, devices, or drugs). Projects typically involve evidence-based literature synthesis, Bayesian interpretation of diagnostic tests, clinical decision analysis, utility assessment or the measurement of patient preferences for health outcomes, cost effectiveness analysis, medical informatics and artificial intelligence in medicine.
The Division provides a clinical decision making consultation service that examines complex management dilemmas in individual patients and provides advice based on literature review and formal decision analysis. Typical applications involve patients who might benefit from anticoagulation but have risk factors for bleeding, patients with multiple co-morbidities facing possible surgery, or patients of unusual age or limited life expectancy.
Edward Saltzman, MD, Chief
Bess Dawson-Hughes, MD
Andrew Greenberg, MD
Joel Mason, MD
Denise Rollinson, MD
Irwin Rosenberg, MD
Robert Russell, MD
The Division of Clinical Nutrition provides patient care, research and teaching in the area of nutrition and nutritional therapeutics. The Division provides evaluation and management of inpatient and ambulatory patients with nutritional disorders. Services for inpatients are provided by the Nutrition Support Service, which offers consultation and management for nutritional and metabolic complications of acute and chronic disease in the hospital. The consultation service also supervises the transition and management of patients requiring home parenteral or enteral nutritional treatment.
Members of the Division comprise the medical component of the multidisciplinary Obesity Consultation Center, which provides a range of medical and surgical treatment options for overweight and obese patients. In addition, in joint ambulatory services with Endocrinology and Gastroenterology, the Division operates specialized clinics in metabolic bone disease, eating disorders, and nutritional complications of gastrointestinal disorders.
Specialized procedures are available for evaluation of patients with changes in body weight and body composition, and for diagnosis and treatment of vitamin and trace mineral disorders. Appropriate use of dietary and vitamin supplements in patients with special nutritional requirements imposed by disease, aging, and other factors is a special interest of this clinical group.
An academic fellowship in Human Nutrition and Metabolism is provided by this Division for those physicians interested in pursuing specialty training in this field.
Ronald Lechan, MD, PhD Acting Chief
Miriam Blum, MD
Lisa Ceglia, MD
Michael Dansinger, MD
Bess Dawson-Hughes, MD
Andrew Greenberg, MD
Caroline Kim, MD
Anastassios Pittas, MD
Richard Siegel, MD
Jeffrey Tatro, PhD
The Division of Endocrinology, Diabetes and Metabolism at Tufts Medical Center offers diagnostic and therapeutic services for patients with a wide variety of endocrine and metabolic disorders including thyroid, hypothalamic/pituitary and adrenal diseases, islet cell tumors, diabetes, lipid disorders, diseases of calcium regulation, osteoporosis and other metabolic bone diseases. Staff physicians work closely with referring primary care physicians, as well as other subspecialty services to coordinate the diagnosis and management of complex endocrine diseases. This multidisciplinary approach and access to on-site ancillary services ensures the excellent, personalized care for each patient. State-of-the-art diagnostic capabilities within the Division include on-site ultrasound, which is used in the evaluation and and management of suspected and confirmed thyroid nodules and thyroid cancer, and on-site Continuous Glucose Monitoring Sensor. The Division also features comprehensive endocrine provocative testing and infusions and an insulin pump program.
The Division has a longstanding interest in neuroendocrinology with extensive investigations into hypothalamic regulatory mechanisms involved in the control of thyroid hormone secretion, neuroimmunology, and the molecular pharmacology and signal transduction of melanocortin receptors. The Division also has a strong research interest in diabetes mellitus, the prevention of obesity, atherosclerosis and coronary artery disease risk factors, and the effects of low glycemic index calorie-restricted diet on the metabolic syndrome, and how diet impacts bone and muscle in older men and women. Research interests also include molecular, cellular and endocrinological regulation of fat cells, mechanisms for the development of thyroid cancer, and nutritional and genetic regulation of plasma lipoprotein metabolism. The Division has been involved in long tern studies of a large kindred with multiple endocrine neoplasia syndrome.
Joel Weinstock, MD, Chief
Peter Bonis, MD
Ian Gan, MD
Moises Gelrud, MD
Kenneth Hung, MD
Douglas Janowski, MD
Marshall Kaplan, MD
Alan Kopin, MD
Hannah Lee, MD
Joel Mason, MD
Lori Olans, MD
Andrew Plaut, MD
Lawton Shick, MD
Kathleen Vivieros, MD
The clinical and research interests of the G.I. staff encompass the entire spectrum of gastroenterologic and liver diseases. There are more than 6800 ambulatory visits per year to a very active G.I. clinic that provides care for referred patients with a wide array of diseases, including inflammatory bowel disease, motility disorders, peptic ulcer disease, liver disease and pancreatic disorders. In addition, the GI Division is an internationally recognized referral center for patients with hepatobiliary disorders, including acute and chronic hepatitis, primary biliary cirrhosis and primary sclerosing cholangitis. The inpatient GI service cares for the sickest patients, those with difficult-to-manage inflammatory bowel disease, pancreatitis, GI bleeding and decompensated liver disease. Many of these latter patients are taken care of by our liver transplantation service that is now the largest in New England. Our endoscopy service is recognized for its expertise in all therapeutic procedures.
All members of the G.I. staff are actively engaged in clinical or basic research. Current clinical studies include (1) treatment of chronic hepatitis C with alpha interferon and ribavirin, (2) pathogenesis of primary biliary cirrhosis and primary sclerosing cholangitis, and their treatment with Methotrexate, Ursodeoxycholic acid, Colchicine, or combinations of these drugs, and new agents such as TNF inhibitors and cytokines, (3) the use of new drugs in the treatment of H. Pylori GI infection, (4) new cytokine inhibitors in the treatment of ulcerative colitis and Crohn's disease and (5) the management of malabsorption in aging. In addition, the G.I. Division has an N.I.H.-funding to address basic research in digestive disease. Research areas include the cloning of various G.I. hormone receptors such as gastrin and cholecystokinin, the developmental biology of polypeptide G.I. hormones, and the role of host secretory immunity in defending against various G.I. pathogens and the pathogenesis of H. pylori infection. Also studied is immune regulation at mucosal surfaces as it relates to inflammatory bowel diseases.
Michael Wagner, MD, Chief
Dineli Ahearn, MD, Associate Chief
Deborah Blazey-Martin, MD
Alison Brennan, MD
Jeanine Carlson, MD
Daniel Chandler, MD
Elaine Choi, MD
Brian Cohen, MD
Paul Duncan, MD
Chloeanne Estrera, MD
David Fairchild, MD
Eileen Hession, MD
Linda Kaplan, MD
Winifred Kender, MD
Richard Kopelman, MD
Gertrude Kramer, MD
Diane Krause, MD
Joan Kross, MD
Mary Lee, MD
Cinthya Marturano, MD
John Mazzullo, MD
Catherine Milch, MD
Julia Murphy, MD
Judith Pinsker, MD
Joseph Rencic, MD
Sarah Schweber, MD
Harry Selker, MD
Myron Siu, MD
Laura Snydman, MD
Steven Spector, MD
Brenda Walkey, MD
Elisabeth Wilder, MD
Ira Wilson, MD
John Wong, MD
The division of General Medicine has a major impact on the Internal Medicine Residency Program. All Internal Medicine interns and residents become members of our primary care practice under the supervision of a dedicated academic preceptor.
Our ambulatory practice is multi-disciplinary, integrating internists with nurse practitioners, nurses, and social workers. The practice emphasizes the three primary aspects of ambulatory Adult Medicine: prevention and screening, chronic disease management, and evaluation and treatment of urgent conditions.
General Medicine also runs the General Medicine Inpatient Service and Medical Consult Services. On the General Medical Service, residents are exposed to a wide variety of acute disease problems and learn how to care efficiently for hospitalized patients. The goal of consult service is to provide General Medicine consultation services to patients on non-medical services. Residents are exposed to the management of medical conditions for patients on the surgical, obstetrical, and psychiatry services. Our staff provides leadership for monthly morbidity and mortality conferences and journal club meetings.
David Snydman, MD, Chief
Geneve Allison, MD
Robert Arbeit, MD
Jorge Bariniaga, MD
Michael Barza, MD
Helen Boucher, MD
Lisa Davidson, MD
Shira Doron, MD
Yoav Golan, MD
Sherwood Gorbach, MD
Jeffrey Griffiths, MD
Jim Hellinger, MD, MPH
Patricia Hibberd, MD, PhD
Linden Hu, MD
Michael Jordan, MD, MPH
Laura Kogelman, MD
Teena Kohli, MD MS
Alexandra Mangili , MD, MPH
Debra Poutsiaka, MD, PhD
Martin Rhee, MD
David Stone, MD
Cheleste Thorpe, MD
Matthew Waldor, MD, PhD
Christine Wanke, MD
Simone Wildes, MD
Jennifer Wolfson, MD
The Division of Geographic Medicine and Infectious Diseases maintains a very large clinical and research base from which the interns and residents have many educational and clinical opportunities. The Division has an inpatient clinical service, and two consultation services, one of which involves the care of patients who have infectious complications from transplantation. The Division has 4000 ambulatory visits in the infectious diseases center which combines general ambulatory infectious diseases care with AIDS primary care, the Travelers Health Service. The division has opportunities for interns and residents to rotate through both inpatient and outpatient areas, and conduct clinical research in small projects as well. The Division has a very strong training program in basic research as well as clinical research and maintains three training grants from the National Institutes of Health. The Division has always maintained an emphasis on clinical and basic training with particular emphasis on integrating basic concepts with diagnostic and therapeutic strategies necessary for an effective clinical practice.
Richard Van Etten, MD, PhD, Chief
Rachel Buchsbaum, MD
Katayoon Goodarzi, MD
Andreas Klein, MD
Hans-Georg Klingemann, MD, PhD
Athan Kuliopulos, MD, PhD
Stuart Levy, MD
Kenneth Miller, MD
Uma Narayanasami, MD
John Nystrom, MD
Hedy Smith, MD, PhD
Kellie Sprague, MD
Gary Strauss, MD
Kathy Theall, MD
Philip Tsichlis, MD
Virginia Zaleskas, MD
Jay-Jiguang Zhu, MD
The Division of Hematology-Oncology maintains one of the larger clinical and research programs at Tufts Medical Center. The Division includes 18 full-time faculty members in addition to clinical and research fellows supported by NIH training grants. Over 1,300 outpatients attend the Hematology and Oncology Clinical Center every month. The Division maintains three inpatient services: the Hematology/Oncology Service, the Leukemia/Bone Marrow Transplantation Service, and the Consultative Service. The Bone Marrow Transplantation (BMT) Unit performs allogeneic, autologous and matched unrelated allogeneic transplants. The biologic response modifier service was one of the first to use interleukins in the therapy of several cancers. The Division's Experimental Therapeutics Programs runs the photophoresis program in conjunction with a major BMT program in the area. Patients have been referred for T-cell lymphoma, GVHD and organ rejection.
The Division's research programs are supported predominantly by research grants from the National Institutes of Health. Pioneering studies have involved interleukins and cytokines, cellular adhesion molecules including P-selectin, CD 43, and the molecular biology of the thrombin receptor. There are numerous clinical research trials available. The Division oversees the major Eastern Cooperative Oncology Group (ECOG) program in the New England area.
Andrew Levey, MD, Chief
Ronald Perrone, MD Associate Chief
Vaidyanathapura Balakrishnan, MD
Anthony Dash, MD
Scott Gilbert, MD
John Harrington, MD
Annamaria Kausz, MD
Samina Khan, MD
Andrei Kouznetsov, MD
Amy Kuhlik, MD
Vandana Menon, MD
Klemens Meyer, MD
Dana Miskulin, MD
Dena Rifkin, MD
Mark Sarnak, MD
Leslie Stevens, MD
Katrin Uhlig, MD
Daniel Weiner, MD
Caring for patients is the core mission of the William B. Schwartz Division of Nephrology. Division members are also highly committed to scientific inquiry and solving problems relating to kidney disease. In addition, the Division is engaged in the education of medical students and residents and provides subspecialty training in Nephrology and post-graduate medical education. Furthermore, Division members are actively involved in service to professional organizations and public policy initiatives.
In 2006, the Division became the home of the editorial offices of the American Journal of Kidney Diseases (AJKD), the official journal of the National Kidney Foundation (NKF). The Division is leading a multi-institution effort to continue to make AJKD the preeminent clinical journal in nephrology. Additionally, Division members are using this opportunity to enhance fellow and staff education in the manuscript writing, review, and operations.
The Division is also the home of the NKF Center for Clinical Practice Guideline Development and Implementation. The mission of the Center is to improve the quality of care of individuals with kidney disease through service to the NKF and research and training in the developing and implementing evidence-based clinical practice guidelines. The Center provides methods support and guidance in developing guidelines commissioned by the NKF in the Kidney Disease Outcomes Initiative (KDOQI) and the Kidney Disease: Improving Global Outcomes (KDIGO) initiative. The Evidence Review Teams at the NKF Center lead work groups of international experts through the process of systematic literature review and produce evidence reports that provide the backbone for evidence-based clinical practice guidelines. These guidelines have led to improvement and standardization in the care of patients with chronic kidney diseases in the US and abroad.
Pulmonary, Critical Care and Sleep
Nicholas Hill, MD, Chief
Walter Baigelman, MD
Carolyn D'Ambrosio, MD
Scott Epstein, MD
Barry Fanburg, MD
Geraldine Finlay, MD
Erik Garpestad, MD
Katherine Hendra, MD
Heidi O'Connor, MD
John Ohman, MD (Allergy)
Ioana Preston, MD
Kari Roberts, MD
Greg Schumaker, MD
Amy Simon, MD
Maher Tabba, MD
John Unterborn, MD
Alexander White, MD
The Pulmonary, Critical Care and Sleep Division has an active inpatient service centered on both the ward service and the medical intensive care unit. Both Pulmonary and Allergy have a consultation service and between the two of them there are seven clinics per week. Specialty clinics include Asthma, Pulmonary Rehabilitation and Pulmonary Hypertension. Pulmonary has an active inpatient Ward Service, and Pulmonary, Critical Care physicians oversee care of patients in the ICU. The division has an interest in Pulmonary Hypertension and performs 75-100 right heart catheterizations per year. There is an active bronchoscopy service, extensive pulmonary function testing facilities and a state of the art 6 bed sleep laboratory.
Several projects supported by the National Institutes of Health and the American Thoracic Society are being carried out in the Pulmonary research laboratories. Many of these involve the use of cellular and molecular biological techniques. Some studies assess the mechanisms of lung injury that occur in respiratory distress syndrome or oxidant exposures. These include research on the effects of cytokines on lung cells and protective methods (cellular superoxide dismutase induction, cellular glutathione evaluation) that are derived to defend against injury. Other studies are concerned with the mechanism of hypoxia induced pulmonary hypertension, including studies of endothelial and smooth muscle cells in culture. Other projects involve studying signal transduction pathways by which circulating vasoactive substances alter responses of the pulmonary vasculature. Other basic investigations are concerned with immunologic responses of the lung and in particular mechanisms of granuloma formation in sarcoidosis. There is also an active Clinical Research group within the division, performing studies related to use of noninvasive ventilation, sleep aspects of clinical care, and pulmonary hypertension diagnostics and therapeutics.
The Allergy section is interested in the immunoregulation of allergic disease, occupational allergy to laboratory animals and the mechanisms of IgE antibody response to allergen.
Timothy McAlindon, MD, Chief
Senada Arabelovic, DO
Robert Kalish, MD
Grace Lo, MD
William Harvey, MD
Janeth Yinh, MD
Over the past several years, the Rheumatology Division has experienced tremendous growth, both clinically and in the laboratory. Clinics are held each day, in the newly renovated Itzhak Perlman Family Arthritis Treatment Center, including a referral based Lyme Disease clinic and a research clinic in rheumatoid arthritis. The consultation service is active. Residents spend assigned time in these activities with a structured teaching program.
A central focus of research within the Division is the elucidation of the role of infectious agents, autoimmunity and cytokines in the pathogenesis of certain rheumatic diseases. Since Lyme disease is one of the few forms of chronic inflammatory arthritis with a proven infectious etiology it serves as a paradigm for much of this research. Projects include the study of the molecular mechanisms of adhesion and penetration of Borrelia and Yersinia and how these organisms cause chronic arthritis. Antigen-T cell interactions in Lyme disease are being investigated in an attempt to understand how particular infectious agents induce tolerance or autoimmunity. Another effort is directed at making recombinant Borrelia proteins and doing T and B cell epitope mapping of the immune response in Lyme disease. Finally, the role of nutritional factors in patients with rheumatoid arthritis is being examined.
For more detailed information on divisions and staff, please visit the Department of Medicine.