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Genomics Research
Genomics research, which is part of the Tufts CTRC Core Laboratory, is available to assist investigators with effective design, genetic data generation, and analysis of genetic clinical research protocols. The services provided include the following:
· Assistance with Study Design, including the issues of sample size, haplotype-tagging single nucleotide polymorphism (SNP) selection, and phenotype definition.
· DNA processing, including extraction (from whole blood, buffy coats, buccal swabs, mouthwashes, hair), quantification (OD260/280, picogreen, etc), re-platting and storage.
· Assistance with SNP genotyping, using low to medium throughput TaqMan base assay platform (ABI 7900HT and BioTrove Open Arrays) and Sample preparation for Next Generation Sequencing (in collaboration with Tufts University Core Facility).
· For Assistance with other Analysis and Design (consult with Core Lab)
We support different study designs that involve unrelated individuals and families, including prospective studies, case-control studies, pharmacogenomic studies, nutrigenomic studies, and meta-analyses of genetic association studies.
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