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Susceptibility to Human Babesiosis

Title Host Genetic Determinants and Pathogenesis of Severe Babesiosis
Therapeutic Area Babesiosis, Tickborne Diseases
Principal Investigator Edouard Vannier, PhD
Min Age 18 Years
Gender Both
Contact Edouard Vannier, PhD
617 636-8526


Babesiosis is an emerging infectious disease in the United States, The disease is caused by a parasite that invades and eventually ruptures red blood cells. The parasite is transmitted by the deer tick but also can be acquired during blood transfusion. Symptoms include fever, fatigue, chills and sweats. In some individuals, the disease is so severe that hospitalization is required. In others, the infection is mild or event silent. The study is designed to identify factors that determine whether a given individual is prone to experience severe or mild babesiosis or no disease at all.

Study Details

Inclusion Criteria

  • A diagnosis of babesiosis
  • 18 years old
  • Ability to read and understand English

Exclusion Criteria

Study Requirements

One research visit for approximately 30 minutes. One time blood draw for a volume of one to four teaspoons of blood.