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Vitamin D for Established Type 2 Diabetes (DDM2 study)

Title Diabetes and Metabolism - Vitamin D for Established Type 2 Diabetes
Therapeutic Area Diabetes
Principal Investigator Anastassios Pittas, MD MS
Min Age 25 Years
Max Age 75 Years
Gender Both
Contact Yan Chu
More Information


The goal of this research study is to see whether taking vitamin D daily can improve the body’s ability to secrete insulin in patients with established type 2 diabetes.

Study Details

Inclusion Criteria

  • Type 2 diabetes mellitus 
  • Willing to take daily vitamin D supplement

Exclusion Criteria

  • Use of diabetes medications other than metformin 
  • History of kidney stones or kidney disease 
  • Use of vitamin D supplement higher than 1000 IU/day and unwillingness to limit vitamin D supplementation dosage to no higher than 800 IU/day for the duration of the study.

Study Requirements

After the Screening visit (which will ast less than 1 hour), qualified participants will visit the clinic 5 times during the 1-year study. Two visits will be 4 hours long and 3 visits will be 30 minutes long. 
Study visits will be scheduled in the mornings. Participants will be required to fast (no food or drink except water) overnight for 8 hours before each visit. 
Study visits will include the following: 
  • Answering questions about your health, diet and physical activity 
  • Measurement of height, weight and blood pressure.-Blood draw and an Oral Glucose Tolerance Test (OGTT), which will last 3 hours.