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Vitamin D for Established Type 2 Diabetes (DDM2 study)
The goal of this research study is to see whether taking vitamin D daily can improve the body’s ability to secrete insulin in patients with established type 2 diabetes.
Type 2 diabetes mellitus
Willing to take daily vitamin D supplement
Use of diabetes medications other than metformin
History of kidney stones or kidney disease
Use of vitamin D supplement higher than 1000 IU/day and unwillingness to limit vitamin D supplementation dosage to no higher than 800 IU/day for the duration of the study.
After the Screening visit (which will ast less than 1 hour), qualified participants will visit the clinic 5 times during the 1-year study. Two visits will be 4 hours long and 3 visits will be 30 minutes long.
Study visits will be scheduled in the mornings. Participants will be required to fast (no food or drink except water) overnight for 8 hours before each visit.
Study visits will include the following:
Answering questions about your health, diet and physical activity
Measurement of height, weight and blood pressure.-Blood draw and an Oral Glucose Tolerance Test (OGTT), which will last 3 hours.