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Title Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)
Therapeutic Area Dry Eye
Principal Investigator Pedram Hamrah, MD
Min Age 21 Years
Gender All
Contact Nancy Gee
617 636 5489


  • To establish the prevalence of neuropathic corneal pain in patients with ocular surface discomfort.
  • To assess the overlap of neuropathic corneal pain with dry eye disease in patients in diseases that are currently thought to be mutually exclusive.
  • To establish the prevalence of subtypes of patients with neuropathic corneal pain or with a neuropathic component of dry eye in patients with ocular surface discomfort.

Study Details

Inclusion Criteria

  • Presents with ocular surface discomfort or for dry eye care
  • Best corrected visual acuity of 20/40 or better in each eye
  • Subject reported duration of symptoms of at least 3 months

Exclusion Criteria

  • Use of contact lenses on the day of the visit
  • Pregnant or nursing
  • Irregular corneas (e.g., ectatic disease, transplantation, or corneal dystrophies)

Study Requirements

One visit