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SPRINT


Title Hypertension - SPRINT
Therapeutic Area High Blood Pressure, Hypertension
Principal Investigator Daniel Weiner, MD MS
Min Age 55 Years
Max Age 85 Years
Gender Both
Contact Sarah Duncan
617-636-9672
More Information http://clinicaltrials.gov/ct2/show/NCT01206062

Overview

About two-thirds of those over age 60 have high blood pressure. Lowering blood pressure further than current practice might help prevent heart disease, stroke, and kidney disease. In addition, high blood pressure can cause changes in memory and thinking as people get older. The purpose of this study is to determine whether lowering blood pressure will reduce the rate of heart disease and stroke, memory decline or worsening of kidney disease in adults over the age of 55 who already have high blood pressure. Specifically, the SPRINT trial will test whether keeping systolic blood pressure (top number in your blood pressure reading) less than 120 mmHg is better than the current recommendation of keeping it less than 140 mmHg. This study does not involve experimental drugs. The trial is approximately 5 years long and participants receive free blood pressure medications for the duration of the study.

Study Details

Inclusion Criteria

  • History of High Blood Pressure

Exclusion Criteria

  • Diabetes
  • History of Stroke
  • Organ Transplant

Study Requirements

During the approximate 5 year duration of this study, visits are held once a month for the first 3 months (1M, 2M and 3M) and from then onward, visits are held every 3 months (6M, 12M, 15M, 18M, etc..). Bloods are collected 4 times in the first year and from then onward, bloods are collected 2 times a year.