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Ultrasound and Patient Function Following ACLR

Title Longitudinal Associations between Femoral Cartilage Ultrasound Outcomes and Patient Reported Outcomes Following Anterior Cruciate Ligament Reconstruction
Therapeutic Area Knee Injuries and Disorders
Principal Investigator Jeff Driban, PhD
Min Age 18 Years
Max Age 35 Years
Gender All
Contact Matt Harkey
617 636-3203


The purpose of this study is to determine the diagnostic, prognostic, and burden of disease performance for a clinically accessible knee cartilage ultrasound assessment in relation to patient reported outcomes in individuals following anterior cruicate ligament reconstruction. We will assess knee cartilage status using ultrasound and patient reported outcomes at several key clinical tine points throughout the first year following anterior cruciate ligament reconstruction. This study is a needed first step to validate knee cartilage outcomes as biomarkers for early decline in patient health.

Study Details

Inclusion Criteria

  • Initial presentation to orthopaedic clinic within 3 months of anterior cruciate ligament injury
  • schedule to undergo unilateral anterior cruciate ligament reconstruction

Exclusion Criteria

  • previous lower extremity surgery
  • history of injury to either leg within 6 months prior to participation
  • diagnosis of any form of arthritis

Study Requirements

6 research visits that coincide with routine clinical follow-ups to your orthopaedic surgeon appointments.