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Accuracy Using Optical Mammography
||Mammography - Accuracy Using Optical Mammography
Mammography, Breast Cancer
||Roger Graham, MD
617 636 7651
The purpose of this project is to study how well near-infrared light (that is, light in the red region and beyond the visible limit in the wavelength range 600-1,000 nm) is at detecting and monitoring breast cancer during treatment.
- Scheduled for routine or diagnostic x-ray mammogram
- Patients with biopsy-proven cancer and scheduled for neoadjuvant cancer therapy
- Pregnant or thinks she might be pregnant
Phase 1: Two images of each breast will be taken followed by dynamic measurements of both breasts done simultaneously during a series of inflation and deflation of pneumatic thigh cuffs. The total measurement will take 30 minutes or less. The optical imaging procedure requires about 1 minute per image. Because two images are acquired for each breast, the total measurement time is about 10 minutes or less. For the dynamic measurement, data will be collected continuously for up to 20 minutes while the breasts are stabilized in the optical mammogram device.
Phase 2: All the same procedure as in Phase 1 with the addition of the following procecures: We will be asking participants to come in and have an optical mammogram done on a regular basis while undergoing neo-adjuvant chemotherapy or hormone therapy according to the schedule below.
For subjects being treated with chemotherapy, they will have an optical mammography:
- Immediately prior (same day) to receiving the chemotherapy, or
- Weekly, if possible, as the schedule allows
For subjects being treated with hormone therapy, they will have an optical mammography:
- Every other week, or weekly, if possible, as the schedule allows