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Title Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients
Therapeutic Area Obesity
Principal Investigator Konstantin Balonov, MD
Min Age 18 Years
Max Age 99 Years
Gender All
Contact Konstantin Balonov, MD
508 380-0433
More Information


Morbidly obese patients scheduled for abdominal surgery duration at least two hours are randomized in two groups, ventilation with high PEEP and recruitment maneuvers or low PEEP and no recruitment. the incidence of postoperative pulmonary complications as well as intraoperative side effects is recorded.

Study Details

Inclusion Criteria

  • Patient scheduled for surgery under general anesthesia
  • BMI ≥ 35 kg/m2
  • Expected duration of surgery ≥ 2 h

Exclusion Criteria

  • Age < 18
  • Previous lung surgery
  • Persistent hemodynamic instability

Study Requirements

Patients are followed up until discharge from the hospital for the maximum duration of five days. Blood and urine samples will be collected intraoperatively and immediately postoperatively in the PACU.