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The Relationship Between Joint Structure and Pain in Osteoarthritis of the Hand

Title Cross-Sectional Observational Study Evaluating the Use of Ultrasound to Evaluate the Hands of People with and without Symptomatic Hand Osteoarthritis to Examine the Extent and Severity of US-Detected Synovitis and the Relationship Between Symptoms and Structural Abnormalities. 
Therapeutic Area Hand Osteoarthritis
Principal Investigator Steven C. Vlad, MD, PhD
Min Age 40 Years
Max Age 100 Years
Gender All
Contact Vivian Deng


The purpose of this study is to learn more about the relationship between synovitis (swelling and inflammation of the joint lining) and pain in persons with symptomatic and non-symptomatic hand osteoarthritis by using ultrasonography (US). 

Study Details

Inclusion Criteria

  • Participants who are at least 40 years old
  • Participants with hand osteoarthritis

Exclusion Criteria

  • History of hand trauma
  • Prior surgery on either hand within the last 6 months
  • Evidence or history of inflammatory arthritis, including but not limited to rheumatoid arthritis, psoriatic arthritis, and uncontrolled or tophaceous gout

Study Requirements

There will be one study visit at which your hands will be examined and evaluated via ultrasound (US). You will be asked to complete questionnaires about your medical conditions and your hand pain.