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The Tree of Life


Title The Tree of Life: Harnessing Placenta Biology for Cardiovascular Disease Research
Therapeutic Area Pregnancy
Principal Investigator Mary Wallingford, PhD
Min Age 18 Years
Max Age 50 Years
Gender Female
Contact Vidya Iyer
617-636-0186
viyer1@tuftsmedicalcenter

Overview

This study is being done to learn more about the placenta’s rich blood supply and the relation between the placenta and family history of heart health. The researchers would also like to find out if this information can be used to help guide long term heart health care. To study this, we would like to collect and compare placentas from subjects who have a family history of heart disease to those who do not have a family history of heart disease.

Study Details

Inclusion Criteria

  • Currently pregnant with single fetus
  • With or without history of heart disease in family
  • No history of heart disease in subject

Exclusion Criteria

  • Adopted or family history unknown
  • History of drug or alcohol use
  • Pregnant with twins or triplets

Study Requirements

The study requires one visit which is considered the day the subject signs the informed consent and completes the eligibility checklist. There are no additional study visits. The first study visit will be conducted along with the subject’s routine clinical appointment. This visit should take approximately 20-30 minutes. 2 additional questionnaires will be completed; a family history questionnaire that can be completed on the same visit day and a family history confirmation questionnaire. To complete this questionnaire the family member with a history of heart disease will be contacted and the questions can be completed by phone or via an automated survey. The placenta will be collected after the subject delivers.