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Retinal Microperimetry


Title Nidek MP-3 Microperimetry in Retinal Disorders
Therapeutic Area Macular Degeneration, Diabetic Eye Problems, Glaucoma
Principal Investigator Nadia K. Waheed
Min Age 18 Years
Gender Any
Contact Nadia K. Waheed
617-636-7950
nwaheed@tuftsmedicalcenter.org

Overview

Microperimetry allows for precise structure-function correlation studies to be performed on the retina. By creating a map of retinal sensitivity and overlaying it onto images of the retina, structure-function correlation can be determined. Already used in common retinal diseases like diabetic retinopathy, microperimetry has proven useful as a diagnostic tool. Studies have shown early changes in retinal sensitivity associated with disease even before there are major clinically apparent changes in the eye. This suggests that there may be subtle changes to eye structure and function before vision is noticeably impaired—better understanding these changes could provide rationale for earlier intervention to prevent deterioration in patient vision. This study seeks to assess possible structural and functional changes over the course of the disease progression in a variety of retinal disorders by using microperimetry in combination with optical coherence tomography imaging. This could allow for earlier detection of diseases, provide rationale for earlier intervention, and provide a means of tracking and managing disease progression.

Study Details

Inclusion Criteria

  • Diagnosis of age-related macular degeneration
  • Diagnosis of diabetic retinopathy
  • Diagnosis of glaucoma

Exclusion Criteria

  • Retina not visible on exam
  • Media opacity in eye
  • Difficulty fixating during imaging

Study Requirements

This study requires one visit lasting about 45 minutes, which cn be completed immediately following a regularly scheduled clinic appointment. Subjects will undergo microperimetry testing, which involves looking into a machine and pressing a button when they see a flash of light. Each microperimetry session lasts about 20 minutes. Then subjects will receive OCT imaging on up to 4 devices. Each OCT imaging session lasts about 5 minutes.