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The Tick Study

Title A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Single-Center, Human Tick Kill Proof-of-Concept Study Evaluating the Safety, Tolerability, and Whole Blood Concentration of TP-05 (lotilaner) in Healthy Volunteers
Therapeutic Area Healthy Volunteers
Principal Investigator Yoav Golan, MD and Linden Hu, MD, PhD
Min Age 18 Years
Max Age 59 Years
Gender Any
Contact
617-636-4714
CTRCappointments@tuftsmedicalcenter.org
More Information https://clinicaltrials.gov/ct2/show/NCT05387083

Overview

Researchers at Tuft Medical Center are seeking healthy volunteers to participate in a study of an investigational drug that may prevent tick bites. 

Study Details

Inclusion Criteria

Between 18 to 59 years old.
 

Exclusion Criteria

Have a history of severe reactions to tick bites.

Currently pregnant or trying to conceive.

Study Requirements

Participants will take one dose of the study drug or a placebo. There will be 10 visits to Tufts Medical Center over the course of up to 301 days. Ticks will be placed on your arm twice during the study to test the drug's effectiveness. The ticks are lab-grown and extensively tested for diseases. Qualified participants who complete all study visits will receive compensation of $2,450.