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The Tick Study


Title A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Single-Center, Human Tick Kill Proof-of-Concept Study Evaluating the Safety, Tolerability, and Whole Blood Concentration of TP-05 (lotilaner) in Healthy Volunteers
Therapeutic Area Healthy Volunteers
Principal Investigator Yoav Golan, MD and Linden Hu, MD, PhD
Min Age 18 Years
Max Age 59 Years
Gender Any
Contact Vidya Iyer
617-636-0186
viyer1@tuftsmedicalcenter.org
More Information https://clinicaltrials.gov/ct2/show/NCT05387083

Overview

Researchers at Tuft Medical Center are seeking healthy volunteers to participate in a study of an investigational drug that may prevent tick bites. 

Study Details

Inclusion Criteria

Between 18 to 59 years old.
 

Exclusion Criteria

Have a history of severe reactions to tick bites.

Currently pregnant or trying to conceive.

Study Requirements

The study involves a single dose of a human version of an investigational drug currently approved to prevent tick bites in dogs or a placebo.  

Participation will involve 5 visits to Tufts Medical Center over the course of 30 days. 

Laboratory reared ticks, tested to be free of all known human diseases will be placed on your arm in a sealed dressing twice during the study to test the ability of the drug to prevent tick bites.