A Safety and Feasibility Study of Percutaneous Delivery of an Arterial VA-ECMO Cannula into the Aorta

This research is being done to study a potential method of improving blood flow and oxygen delivery to the organs of patients on VA-ECMO. This study involves positioning the return cannula in the aorta, which is the main artery that carries blood away from the heart. We aim to prove that returning oxygenated blood to the aorta is safe and feasible. We also aim to better understand the effects that this method may have on the forces that affect blood flow and heart function.  

Inclusion Criteria

• Clinically indicated need for peripheral cannulation of VA-ECMO via the femoral approach as determined by the care-providing team due to cardiogenic shock or respiratory failure.
• Male or female between 18-75 years of age
• Patient or legally authorized representative provides informed consent

Exclusion Criteria

• ACS requiring emergent coronary intervention
• Cardiac arrest requiring cardiopulmonary resuscitation
• Cardiac surgery within 72 hours prior to enrollment

Study Requirements

No additional research visits are required. No additional blood collections or imaging.