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Title Sleep for Stroke Management And Recovery Trial
Therapeutic Area Stroke
Principal Investigator Lester Y. Leung
Min Age 18 Years
Gender All
Contact Emma Jost-Price
More Information


The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.

Study Details

Inclusion Criteria

  • Acute Ischemic Stroke or TIA within prior 14 days.

Exclusion Criteria

  • Current use of positive airway pressure (CPAP) machine or within month prior to stroke
  • Current receipt of oxygen supplementation

Study Requirements

Participants will be randomized to receive a CPAP machine or no CPAP machine and will be followed for six months after their stroke to assess for functional outcomes and stroke recurrence.