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Fetal MRI study of Twin-Twin Transfusion Syndrome
||Evolution of Cerebral Development in Twin-Twin Transfusion Syndrome (TTTS)
Twin-Twin Transfusion Syndrome
The study includes 30 pregnant women with twin pregnancy - 15 carrying twin fetuses that have been prenatally diagnosed with twin-twin transfusion syndrome (TTTS), and 15 carrying healthy twin fetuses. These women may be offered a fetal MRI scan at no cost to the women. Dr. Tarui will look for differences and changes in the fetal brains with TTTS compared to unaffected twin fetuses.
The study also includes children of women who participate in the study. Children will be followed up after the birth and their neurodevelopmental outcome will be precisely recorded by battery of neurodevelopmental testing at 18 month of age.
The study’s goal is to establish anatomical landmarks for fetal brain development in TTTS that can subsequently predict future neurodevelopmental outcome of affected children.
- Pregnant women with identical twin pregnancy
- Pregnant women with twin pregnancy diagnosed with twin-twin transfusion syndrome
- Fetus/infant with other major malformation such as congenital heart disease.
- Fetus/infant with chromosomal anomalies or known genetic disorders
One (or two) fetal MRI study (~2h) at no cost