Back to Results

Chloroprocaine vs. Bupivacaine for Cervical Cerclage

Title A Randomized Controlled Trial of Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage
Therapeutic Area Obstetric Anesthesia
Principal Investigator Dan Drzymalski, MD
Min Age 18 Years
Max Age 45 Years
Gender Female
Contact Dan Drzymalski, MD
617 636-2091


This is a randomized controlled trial which compares the effect of chloroprocaine versus bupivacaine for cervical cerclage.

Study Details

Inclusion Criteria

  • ASA classification II or III
  • Simple prophylactic cervical cerclage
  • Planning neuraxial anesthesia

Exclusion Criteria

  • Complex cervical cerclage (e.g. bulging bag)
  • Contraindication to neuraxial anesthesia
  • Known hypersensitivity to chloroprocaine (a.k.a. Ester allergy) or bupivacaine (a.k.a. Amide allergy)

Study Requirements

Only one research visit is required; it occurs on the day of cervical cerclage.