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Dr. Mary Wallingford is 2021 Tufts MC PEW Applicant

Dr. Mary WallingfordMary Wallingford, PhD, a PI at both the Mother Infant Research Institute (MIRI) and the Molecular Cardiology Research Institute (MCRI), was chosen to submit a PEW Scholars Program grant proposal for 2021. Tufts Medical Center submitted only one application in response to the  announcement. The Internal Selection Committee chose Dr. Wallingford as the institution’s applicant. The award is for $75,000 (total costs) each year for four years. 

The Pew Scholars Program in the Biomedical Sciences provides funding to young investigators of outstanding promise in science relevant to the advancement of human health. The program makes grants to selected academic institutions to support the independent research of outstanding individuals who are in their first few years of their appointment at the assistant professor level.

The title of the proposal is “Placental Vascular Development in Hereditary Hemorrhagic Telangiectasia (HHT).”  HHT is a debilitating disorder that results from developmental abnormalities in blood vessels.  Increased pressure in the abnormal vessels leads to heightened strain and hemorrhage. It remains largely unknown how the hallmarks of HHT observed in numerous organs, including the lung, liver, retina, and brain, affect the maternal cardiovascular system or the placenta. Dr. Wallingford’s lab aims to address this knowledge gap by generating basic science research models that can be used to study the role of HHT genes in pregnancy and by testing the overall hypothesis that endothelial expression of HHT genes is required for normal development of placental vasculature.