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clinical trial
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This phase II trial tests how well an imaging procedure called fludeoxyglucose F-18 (FDG) positron emission tomography/computed tomography (PET/CT) works in predicting response to standard of care chemotherapy prior to surgery in patients with HER2-positive stage IIa-IIIc breast cancer. FDG is a radioactive tracer that is given in a vein before PET/CT imaging and helps to identify areas of active cancer. PET and CT are imaging techniques that make detailed, computerized pictures of areas inside the body.
clinical trial
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This study aims to learn more about the investigational drug, ASTX727, and another drug, venetoclax, when given in combination. It also aims to evaluate potential pharmocokinetics (PK) interactions for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who are age 75 years or older, or who have comorbidities that preclude use of intensive induction chemotherapy.

The primary purpose of the study is to rule out drug-drug interactions between ASTX727 and venetoclax combination therapy.
department
The understanding of cancer is growing every day and our clinicians are making a significant impact on how the world researches, teaches and delivers care to improve quality and quantity of life.
Announcements
November 7, 2022
Tufts Medical Center patient, triathlete overcomes brain aneurysm to complete Ironman competition.
clinical trial
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This is a single center prospective cohort study. The cohort (interventional) patients will receive the study intervention (ABCLO). The control group retrospective patients that were previously managed at the same center, regardless of the technique or the device used to close the OA.
clinical trial
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The primary goal of this study is to improve our understanding of changes in skeletal muscle mass in the arms and the legs during a hospitalization for advanced HF. We plan to measure muscle thickness with an ultrasound machine in two locations on the body (the outer thigh and the upper arm muscle, of the dominant side) from the time a patient is first admitted to the ICU with HF as well as before and after any surgical HF therapies.
department
The Department of Ophthalmology and New England Eye Center makes healthier possible with expert diagnosis and treatment of eye diseases and visual problems. Beyond our clinical care, we’re leading the way to the future of ophthalmic care through training and education programs, eye research and ophthalmic technology development.
Articles
October 19, 2021
From screening mammograms to second opinions and advanced breast surgery, we understand the unique needs and opportunities for managing breast health and disease. Through our clinical collaboration with Tufts Medical Center Cancer Center in Stoneham, we bring a high level of breast care services locally.
clinical trial
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This is a clinical study that explores the effects of Tai Chi or Wellness Education on the gut bacteria of patients with Osteoarthritis. Our intervention is aimed at decreasing pain and improving quality of life for osteoarthritis patients.

To measure bacterial changes, participants stool samples will be collected and analyzed.These results will help determine mechanisms between bacteria, pain and behavioral pathways as well as progress future research to the potential disease-modifying role of mind-body approaches.
department
The Department of Neurology is at the forefront of treating neurological diseases, uncovering their root causes, and training upcoming neurologists to do the same. When our specialty lies in treating an entire system inclusive of nearly 85 billion neurons, we must collaborate with experts from nearly every branch of medicine to create indisputable improvements in patients’ lives.