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This is a phase 2, randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of atrasentan vs placebo while on background therapy with SGLT2i in subjects with IgAN. The primary efficacy assessment is the change from baseline in proteinuria (UPCR) at week 12. Eligible subjects who are enrolled in the study will be randomly assigned in a 1 to 1 ratio to either sequence AB or sequence BA.
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Apply for the neurology residency program at Tufts Medicine Tufts Medical Center in Boston and advance your career in neurology by learning from top doctors and surgeons.
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The Department of Medicine helps us stand tall as one of the country’s leading health systems. While we take great pride in celebrating our department’s accomplishments, it’s our commitment to training tomorrow's primary care doctors, hospitalists and subspecialists that moves the needle of clinical care forward.