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This is a single site, prospective, cross-sectional, controlled clinical study on a total of 66 subjects. The subjects are divided into two groups: HS non-responders (33 subjects) and HS responders (33 subjects). After completion of questionnaires, the subjects will undergo DED testing and functional nerve testing. Subjects who qualify will be dispensed 4 weeks of preservative free artificial tears and instructed to instill one drop into each eye twice daily.

clinical trial
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Status Epilepticus(SE) is a serious condition that needs fast treatment to stop the seizures and prevent permanent brain damage. The purpose of this research is to find out if ganaxolone can stop or decrease the seizure activity in participants who have SE and if ganaxolone is safe compared to placebo when given to participants who are on other anti-seizure medications.

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Our researchers at the Center for the Evaluation of Value and Risk in Health (CEVR), including CEVR Director Peter J. Neumann, ScD, frequently contribute their knowledge to a wide range of prestigious, peer-reviewed journals.
clinical trial
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We propose to develop an economic in-office pain tests that may help screen and differentiate patients with neuropathic corneal pain (NCP) that could be used at any ophthalmic office. These five in-office pain tests include response with filter glasses, moisture googles, cold saline, hypertonic saline and topical proparcaine.

clinical trial
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The cornea (window in the front of your eye) is made up of many nerves with important regions that allow you to feel sensations like, heat, cold, pressure and vibration. It is well known that many ocular surface disorders, such as dry eye disease (DED), neurotrophic keratitis and post-herpetic neuralgia, affect corneal nerve structure, which can be detected by a special type of eye imaging called ‘In-vivo Confocal Microscopy (IVCM)’. However, the relationship between eye symptoms, signs and abnormal corneal nerve functions are not yet well understood.

clinical trial
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The primary goal of this study is to improve our understanding of changes in skeletal muscle mass in the arms and the legs during a hospitalization for advanced HF. We plan to measure muscle thickness with an ultrasound machine in two locations on the body (the outer thigh and the upper arm muscle, of the dominant side) from the time a patient is first admitted to the ICU with HF as well as before and after any surgical HF therapies.

department
Since our first class in 1893, the Department of Surgery has pioneered possibilities across the full spectrum of surgical illness. We're leading the way in surgical care, from minimally invasive techniques to transplant surgery.
department
The Department of Neurosurgery performs more than 1,700 procedures a year for patients living with high-risk brain tumors, complex spinal cord injuries and disorders presenting from nearly every branch of medicine. Our hands-on approach to patient care is mirrored in our immersive, seven-year residency program, where we prepare tomorrow’s neurosurgeons.
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The mission of our program is to train a diverse workforce of compassionate, empathetic, respectful and competent general pediatricians and subspecialists who strive to be life-long learners through evidence-based medicine in both urban and community settings.
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