Geographic Medicine and Infectious Diseases
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Alysse Wurcel, MD, MS
Attending Physician; Assistant Professor, Tufts University School of Medicine
Department + Services
Medicine, Geographic Medicine and Infectious Diseases
Clinical Focus Areas
Infectious diseases, HIV, hepatitis C, HIV pre-exposure prophylaxis, sexually transmitted diseases
Research Focus Areas
HIV, hepatitis C
Seeing Patients In
Tufts Medical Center
Biewend Building, 3rd Floor
800 Washington St., #238
Boston, MA 02111
Phone #: 617-636-7010
Fax #: 617-636-7100
Hodges J, Reyes J, Campbell J, Klein W, Wurcel A. Successful Implementation of a Shared Medical Appointment Model for Hepatitis C Treatment at a Community Health Center. J Community Health. 2018 Aug 21;
Wurcel AG, Burke DJ, Wang JJ, Engle B, Noonan K, Knox TA, Kim AY, Linas BP. The Burden of Untreated HCV Infection in Hospitalized Inmates: a Hospital Utilization and Cost Analysis. J Urban Health. 2018 Aug;95(4):467-473.
Wurcel AG, Burke D, Skeer M, Landy D, Heimer R, Wong JB, Chui KKH, Stopka TJ. Sex work, injection drug use, and abscesses: Associations in women, but not men. Drug Alcohol Depend. 2018 Apr 1;185:293-297
Oh DHW, Wurcel AG, MS, Tybor, DJ, Burke D, Menendez, ME, Salzler MJ. Increased Mortality and Reoperation Rates After Treatment for Septic Arthritis of the Knee in People Who Inject Drugs: Nationwide Inpatient Sample, 2000-2013. Accepted March 2018 Clinical Orthopedics and Related Research
Wurcel AG, Burke DJ, Skeer M, Landy D, Heimer R, Wong JB, Chui KKH, Stopka TJ. Sex Work, Injection Drug Use and Abscesses: Associations in Women, But Women. Epub Feb 2018 Drug and Alcohol Dependence.
Goulart MA, Wurcel AG, Stopka TS. Investigating the Geographic Distribution of Shigellosis Among Men and Women in Massachusetts: Possible Implications for Men Who Have Sex With Men. Sexually Transmitted Diseases, 2018. March;45(3): 183-185
Wurcel AG, Yu S, Pacheco M, Warner K. Contracts with people who inject rugs following valve
surgery: Unrealistic and misguided expectations. J Thorac Cardiovasc Surg. 2017. Dec; 154(6): 2002
Wurcel AG, Chen DD, Chui KKH, Knox TA. “Tweak your Order Set!” Implementation of Modified Laboratory Order Set Improved Hepatitis C Virus Screening Rates in People Living with Human Immunodeficiency Virus. Open Forum Infections Diseases. May 16 2017; 4(2)
Mukerji SS, Misra V, Lorenz D, Cervantes-Arslanian AM, Lyons J, Chalkias S, Wurcel A, Burke D
Venna N,Morgello S, Koralnik IJ, Gabuzda D. Temporal Patterns and Drug Resistance in CSF Viral
Escape AmongART-experienced HIV-1 Infected Adults. JAIDS 2107 March 21.
Wurcel AG, Anderson JE, Chui KKH, Skinner S, Knox TA, Snydman DR, Stopka TJ. Increasing Infectious Endocarditis Admissions among Young People Who Inject Drugs. Sept 2016 Open Forum Infections Diseases
Goulart M and Wurcel AG. Shigellosis in Men who have sex with Men: An Overlooked Opportunity to Counsel with Pre-Exposure Prophylaxis for HIV. International Journal of STDs and AIDS 2016 Nov;27(13):1236-38
Wurcel AG, Chen DD, Fitzpatrick RE, Grasberger PE, Kirshner CH, Anderson JE, Chui KKH, Knox TA. Hepatitis C Screening in People with Human Immunodeficiency Virus: Lessons Learned from Syphilis Screening. Open Forum Infections Diseases 2016 Feb 12; 3(1). Ofv215
Wurcel AG, Merchant E, Clark R, Stone DR. Emerging and Under-Recognized Complications of Illicit Drug Use. Clinical Infectious Diseases Dec 15 2015; 61 (12): 1840-1849
Dr. Wurcel completed her undergraduate education at Tufts University. She is a graduate of University of Pennsylvania School of Medicine and received a Masters in Clinical Research from the Sacker School of Graduate Biomedical Sciences at Tufts University School of Medicine. In addition to her faculty position in the Department of Geographic Medicine and Infectious Diseases, she is an Assistant Professor in the Department of Community Medicine and Public Health at the Tufts University School of Medicine. She has a weekly HIV/HCV co-infection clinic and also treats people with HIV and HCV mono-infection. Once a month in her co-infection clinic, she sees patients with Dr. Hannah Lee of the GI department.
Her research interests include treatment of Hepatitis C Virus in people considered "tough to treat" including people who inject drugs (PWID), people in the criminal justice system and people with HIV (PLWH). She is the co-investigator of the Tufts REACTs Study (Responds to the Epidemic of hepatitis C Together), a mixed methods project aimed at assessing HCV treatment readiness in young PWID. This study was awarded funding through the Tufts Institute for Innovation in 2015. She is the PI on a Bristol-Myers Squibb study in a clinical trial of HIV medication called an HDAC Inhibitor. Tufts Medical Center is the only hospital in Boston to offer this clinical trial. She also has funding to conduction quality improvement studies on increasing annual HCV antibody testing in PLWH who were Hepatitis C Antibody negative on entry into HIV care.
Dr. Wurcel was recently named to the Tufts Institute of Innovation Affiliates. Affiliates are active members of the TII community
they have access to TII lab space, are invited to participate in TII Project Review meetings, and can extend their three-year appointment after its expiration by securing external funding for their projects.