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Athan Kuliopulos, MD, PhD

Programs + Specialties
Training + Education Johns Hopkins University School of Medicine; Tufts Medical Center
Board Certifications Hematology, Internal Medicine
NPI # 1285740969
Gender Male
Accepted Insurances View Accepted Insurances at Tufts Medical Center

Protease-activated receptors (PARs) are a unique class of G protein-coupled receptors that play critical roles in thrombosis, inflammation, and vascular biology. The PARs are cleaved by thrombin and other proteases at a specific peptide bond to expose a new N-terminus that binds to the body of the receptor in an unusual intramolecular mode.

A major interest of our research group is to study the molecular mechanism of protease activation of the PARs and the subsequent signaling in vascular cells and in cancer.

Tufts Medical Center
800 Washington St., #5609
Boston, MA 02111
Phone: 617-636-8482