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David DeNofrio, MD Accepting New Patients Virtual Appointments Available

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Programs + Specialties
Training + Education Tufts University School of Medicine; Barnes-Jewish Hospital; Duke University Medical Center
Board Certifications Internal Medicine, Cardiovascular Disease
NPI # 1679679997
Gender Male
Accepted Insurances View Accepted Insurances at Tufts Medical Center

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Tufts Medical Center
South Building, 6th Floor
800 Washington St.
Box 5931
Boston, MA 02111
Phone #: 617-636-8068
Fax #: 617-636-6030

2021, "Top Doctor", Boston Magazine
2020, "Top Doctor," Boston Magazine
2018/2019, "Top Doctor," Boston Magazine
2017, "Top Doctor," Boston Magazine
2015, "Top Doctor," Boston Magazine
2014, "Top Doctor," Boston Magazine
2013, "Top Doctor," Boston Magazine
2012, "Top Doctor," Boston Magazine
2012, "Top Doctor" and in top 1% in the nation in his specialty, U.S. News & World Report

David DeNofrio, MD is the Medical Director of the Advanced Heart Failure Program at Tufts Medical Center which has performed the most heart transplants in New England over the past five years. He is also an Associate Professor of Medicine at Tufts University School of Medicine, a longtime member and current Fellow of the American College of Cardiology and board certified in Internal Medicine, Cardiovascular Disease and Advanced Heart Failure/Transplant Cardiology.

Boston Magazine Top Doctors 2023

2023 “Top Doctors” at Tufts Medical Center

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Boston Magazine 2022 Top Doctors

2022 “Top Doctors” at Tufts Medical Center

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Markeith and his son

A life saving heart

Read Markeith's story
Top Doctor 2021

2021 “Top Doctors” at Tufts Medical Center

See our Top Doctors
Top Doctors Boston Magazine 2020

2020 “Top Doctors” at Tufts Medical Center

See our Top Doctors
Hassan Rastegar, MD, Senior Cardiothoracic Surgeon at Tufts Medical Center; Philip Carpino, Chief Physician Assistant at Tufts Medical Center; and Catherine Craig, RN, Clinical Service Leader at Tufts Medical Center, participate in the 500th heart transplant at Tufts MC on June 6, 2018.

500th heart transplant completed at Tufts MC

Learn about the history of heart transplants at Tufts MC
Frank Hewitt the day after a heart transplant

Frank Hewitt's story: Up in the air months after transplant.

See his amazing jump
A drawing of health care for Tufts Medical Center in downtown Boston, MA.

Tufts Medical Center ranks among top-10 heart transplant centers in the United States for 2016.

Top 10 Heart Transplant Program
A drawing of cardiology for Tufts Medical Center in downtown Boston, MA.

Tufts Medical Center breaks New England record with 38th heart transplant.

Record 38th heart transplant
Boston Magazine 'Top Doctor' Award 2015

Boston magazine honors 2015 “Top Doctors” at Tufts Medical Center.

2015 Boston magazine Top Doctors
Pat and Bob both received heart transplants at Tufts MC's CardioVascular Center in Boston.

Pat and Bob's story: Tufts MC cardiac transplant patients beat the odds and create a new foundation for family support - HeartBrothers.

Read how two families joined to help others
Surgeons at Tufts Medical Center in Boston.

Tufts Medical Center ranks first in Massachusetts in adult heart transplants.

Tufts Medical Center ranked first
Heart transplant recipient hugging his donor's mother

Chronicle: The heart chooses the person

Watch the bond between donor's family and recipient
Larry and his daughter Melissa

Chronicle: A special relationship

Watch Big Lar's story
A scientific image of a heart.

There are hundreds of thousands of people in the U.S. on organ transplant wait lists. Learn what you can do to help.

Learn what you can do
Dr. David DeNofrio listening to a patients heart.

Patients receive heart transplant and new life

Watch their stories
Boston Magazine 'Top Doctor' Award 2017

Boston Magazine honors 2017 “Top Doctors” at Tufts Medical Center.

2017 Boston Magazine Top Doctors
Dr. Clarissa Yang on the cover of 2019 Boston Magazine Top Doctor issue.

2019 “Top Doctors” at Tufts MC and Tufts Medical Center

See our Top Doctors
Five white stars

What do the star ratings on physician profiles mean?

Learn about the program