Back to Results

Diana W. Bianchi, MD


Research Interests Prenatal diagnosis, fetal treatment, Down syndrome
Training + Education Stanford University School of Medicine; Children's Hospital, Boston
Board Certifications Clinical Genetics, Neonatal-Perinatal Medicine, Pediatrics
NPI # 1578656690
Gender Female
Language(s) French

Honors + Awards

2014, Appointed Search Committee Member, Director of Extramural Research, NICHD

2013, "Top Doctor," Boston Magazine<

2013, Elected to membership of the Institute of Medicine

2013, Received the NIH Senior Investigator Award for the International Federation of Placenta Associations

2012, "Top Doctor," Boston Magazine

2012, "Top Doctor" and in top 1% in the nation in her specialty, U.S. News & World Report

2012, Received the Duane Alexander Award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

2012, Received the Christopher Columbus Spirit of Discovery Award, Tufts University

2010, Elected Member, Association of American Physicians (AAP)

2008-2009, Hedwig van Ameringen Executive Leadership in Acad. Med. Progr. (ELAM)

2008, Corresponding Member, National Academy of Medicine, Argentina

2006, Honorary Member, American Pediatric Surgical Association

2004, Kristine Sandberg Knisely Award, University of PA School of Medicine

2003, Distinguished Faculty Award, Tufts University School of Medicine

2002, Honorary Member, Society for Maternal-Fetal Medicine

1996, Zucker Prize for Outstanding Faculty Research, Tufts Univ. Sch. of Med.

1990-1992, Basil O'Connor Starter Scholar Research Award, March of Dimes

Publications + National Presentations

1. Guedj F, Bianchi DW. Noninvasive prenatal testing creates an opportunity for antenatal treatment of Down syndrome. Prenat Diagn. 2013;33:614-618.

2. Bianchi DW. From prenatal genomic diagnosis to fetal personalized medicine: progress and challenges. Nature Medicine 2012;18:1041-1051.

3. Bianchi DW. Fetal genes in mother's blood. Nature 2012;487:304-305.

4. Devaney SA, Palomaki GE, Scott JA, Bianchi DW. Noninvasive fetal sex determination using cell-free fetal DNA: systematic review and meta-analysis. JAMA 2011;306:627-636.

5. Hui L, Bianchi DW. Cell-free fetal nucleic acids in amniotic fluid. Hum Reprod Update 2011;17:362-371.

6. Koide K, Slonim DK, Johnson KL, Tantravahi U, Cowan JM, Bianchi DW. Transcriptomic analysis of cell-free fetal RNA suggests a specific molecular phenotype in trisomy 18. Hum Genet 2011;129:295-305.

7. Walt DR, Kuhlik A, Epstein SK, Demmer LA, Knight M, Chelmow D, Rosenblatt M, Bianchi DW. Lessons learned from the introduction of personalized genotyping into a medical school curriculum. Genet Med 2011;13:63-66.

8. Bianchi, DW. From Michael to microarrays: 30 years of studying fetal cells in maternal blood. Prenat Diagn 2010;30:622-623.

9. Maron JL, Alterovitz G, Ramoni M, Johnson KL, Bianchi DW. High-throughput discovery and characterization of fetal protein trafficking in the blood of pregnant women. Proteomics Clin Appl 2009;3:1389-1396.

10. Slonim DK, Koide K, Johnson KL, Tantravahi U, Cowan JM, Jarrah Z, Bianchi DW. Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses. Proc Natl Acad Sci USA 2009;106:9425-9429.

Professional Memberships

2012-2016, National Advisory Child Health and Human Development Council, National Institutes of Health

2007-present, Editor-in-Chief Prenatal Diagnosis

2007-2012, Council Member, American Pediatric Society

2006-2010, President, International Society for Prenatal Diagnosis

2002-2006, Secretary, International Society for Prenatal Diagnosis

2002-2005, Member, Board of Directors, American Soc. of Human Genetics

2002-2005, Council Member (Genetics), Society for Pediatric Research Council (Genetics)

1999, President, Perinatal Research Society

Research Grants

William Randolph Hearst Foundation
This grant will fund the full renovation of postdoctoral research facilities in the Mother Infant Research Institute
Verinata Health, Inc.
Antenatal Treatment to Improve Neurocognition in Fetuses with Down syndrome.
The goal of this project is to use the information in the human amniotic fluid transcriptome to develop novel treatment strategies that could be tested in a pregnant murine model of Down syndrome to determine if treatment improves neurocognition in affected pups.
Role: Principal Investigator

NIH/NICHD (R01HD42053)
Feto-Maternal DNA/RNA Trafficking: Biology and Applications.
The goal of this project is to identify genes that are differentially expressed in human fetuses with aneuploidy and anomalies, and to apply that information to the development of noninvasive prenatal diagnostic tests and new fetal treatments.
Role: Principal Investigator

NIH/NICHD (R01HD058880)
Translational Bioinformatics for Human Developmental Genomics.
The goal of this project was to develop better ways of annotating genomic information for application in fetal, perinatal, and neonatal research.
Role: Co-Investigator

R21 NIH/NHGRI (R21HG004865)
Assessing the Impact of DTC Genetic Testing to Inform Policy Development.
The goal of this project was to assess the accuracy of internet-based claims regarding non-invasive direct to consumer fetal gender testing, and to develop recommendations for public policy in this rapidly evolving area.
Role: Co-Investigator

NICHD T32 HD049341-05
Physician and Scientist Training in Developmental Genetics
This was a training grant that funded the stipends for three pre-doctoral and three post-doctoral trainees.
Role: Principal Investigator

NIH/NICHD (R01HD049469)
The Role of Fetal Cell Microchimerism in Maternal Repair.
The goal of this project was to explore the hypothesis that as a result of pregnancy, females acquire a population of progenitor cells that have regenerative potential, especially in the adult lung.
Role: Principal Investigator