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Jessica Paulus, ScD


Training + Education Haverford College; Harvard School of Public Health
Gender Female

Honors + Awards

2015, Teaching Award, Principles and Practice of Clinical Research, Harvard Medical School
2015, Tufts Medical Center Travel Award
2014, Honorary Professor, Universidad de San Martín de Porres, Lima, Peru
2008, 2010-11, Nominee, Marquand Award Exceptional Advising & Counseling, Harvard College
2008, AACR-Busch Scholar-in-Training Award, AACR Annual Meeting
2007, Travel Award, National Lung Cancer Partnership Annual Meeting
2007, Nominee, Levenson Memorial Prize for Teaching Excellence, Harvard College
2006, Scholar-in-Training Award, AACR Frontiers in Cancer Prevention Research
2005-2009, Certificates of Distinction in Teaching, Harvard College
1999, Biology Departmental honors, Haverford College
1998, Phi Beta Kappa, Early election, Haverford College

Publications + National Presentations

1. Paulus JK, Asomaning K, Kraft P, Johnson BE, Lin X, Christiani DC. Parity and risk of lung cancer in women. Am J Epidemiol. 2010 Mar 1;171(5):557-63. Epub 2010 Jan 31.

2. Paulus JK, Zhou W, Kraft P, Johnson BE, Lin X, Christiani DC. Haplotypes of estrogen receptor-beta and risk of non-small cell lung cancer in women. Lung Cancer. 2010 Jul 22.

3. Dahabreh IJ, Paulus JK. Association of episodic physical and sexual activity with triggering of acute cardiac events. JAMA. March 23/30, 2011, Vol 305, No 12.

4. Dahabreh IJ, Sheldrick RC, Paulus JK, Mei Chung M, Varvarigou V, Jafri H, Rassen JA, Trikalinos TA, Kitsios GD. Do observational studies using propensity score methods agree with randomized trials on the efficacy of treatments for acute coronary syndromes? Eur Heart J. 2012 Aug;33(15):1893-901.

5. Paulus JK, Roberts KE. Oestrogen and the sexual dimorphism of PAH: a translational challenge. Eur Respir J. 2013 May; 41(5):1014-6.

6. Paulus JK, Dahabreh IJ, Balk EM, Avendano EA, Lau J, Ip S. Opportunities and challenges in using studies without a control group in comparative effectiveness reviews. Res Synth Methods. 2014 Jun;5(2):152-61. doi: 10.1002/jrsm.1101. Epub 2013 Oct 23 (PMID: 26052654).

7. Paulus JK, Shah, ND, Kent DM. All else being equal, men and women are still not the same: using risk models to understand gender disparities in care. Circ Cardiovasc Qual Outcomes. 2015 May;8(3):317-20. (PMID: 25901046, PMCID: PMC4440837)

8. Paulus JK, Rosenberg AS. Breast cancer and venous thromboembolism: timing matters. Blood (in press).

9. Paulus JK, Switkowski KM, Molly Connors M, Buchsbaum RJ, Allison GM, Freund KM, Blazey-Martin D. Where is the leak in the pipeline?: An investigation of gender differences in academic promotion at an academic medical center. Perspectives in Medical Education [in press].

10. Paulus JK, Wessler BS, Lai LLY, Lundquist C, Raman G, Lutz JS, Kent DM. A Field Synopsis of Sex in Clinical Prediction Models for Cardiovascular Disease. Circ Cardiovasc Qual Outcomes [in press].


Jessica Paulus, ScD is an Assistant Professor of Medicine at Tufts University and serves as the Associate Director of the Clinical and Translational Science Graduate Program at the Tufts Sackler School. Dr. Paulus graduated with a BS in Molecular and Cellular Biology from Haverford College and a ScD in Epidemiology from the Harvard School of Public Health. Her broad research interests include the study of sex differences in chronic disease epidemiology, and the application of novel methods to address bias in observational data.

Her current research is focused on understanding sex and gender differences in cardiovascular disease in terms of risk, treatment patterns, disease progression and treatment response. As a member of the Tufts Predictive Analytics and Comparative Effectiveness (PACE) Center, she is currently investigating the role of sex in clinical prediction models for cardiovascular and cerebrovascular disease outcomes.

Dr. Paulus is also actively involved in public health and clinical research education, serving as an instructor, curriculum developer and trainer of other public health faculty in novel teaching methods. She is the recipient of a 2012 Tufts Innovates! grant to promote integration in the teaching of advanced epidemiology and biostatistics topics by developing case studies and supporting faculty collaboration. She currently teaches courses in epidemiologic methods in the Clinical and Translational Science Training Program at the Sackler School of Graduate Biomedical Sciences at Tufts University, the Public Health and Professional Degree Programs and Tufts University School of Medicine, and Harvard Medical School. She is also involved in the development of clinical research training programs in various international settings, including Brazil, Peru, Saudi Arabia, Portugal, Ethiopia, Rwanda, Uganda and Nigeria.

Research Focus

Dr. Paulus's primary research interests include the use of epidemiologic methods to evaluate sex differences in chronic disease incidence, prognosis and treatment response, as well as inappropriate healthcare variations, or disparities. Her current research is focused on cardiovascular and cerebrovascular diseases that affect women and men differently in terms of risk, pathophysiological features and disease progression. Dr. Paulus is interested in the role of reproductive, hormonal and other gender-related risk factors in driving differences in risk and outcomes of these conditions. During her doctoral training at the Harvard School of Public Health, she conducted both case-control and prospective cohort analyses of reproductive and hormonal predictors of lung cancer risk and survival in women using hospital-based observational studies. As a member of the Tufts Predictive Analytics and Comparative Effectiveness (PACE) Center, Dr. Paulus is investigating the role of sex in clinical prediction models for cardiovascular and cerebrovascular disease outcomes. In particular, they are interested in exploring the potential for CPMs to support appropriate gender-specific clinical care decisions.