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Johanna M. Seddon, MD, ScM accepting new patients


Programs + Specialties
Research Interests Dr. Seddon’s special research expertise is in evaluating and discovering the causes of macular degeneration, and the implications for prevention and cures. She has had continuous funding from the NIH and several retina foundations for her work in both the genetic components of this disease, as well as the environmental causes.
Training + Education University of Pittsburgh School of Medicine; Tufts Medical Center; Massachusetts Eye and Ear Infirmary
Board Certifications Ophthalmology
NPI # 1699753681
Gender Female
Accepted Insurances View Accepted Insurances at Tufts MC + Floating Hospital

Locations + Directions

New England Eye Center - Boston
800 Washington St., #450
Boston, MA 02111
Phone #: 617-636-9000
Fax #: 617-636-1124

Honors + Awards

2013 Distinguished Alumni Fellow Award, University of Pittsburgh Alumni Association
2013 Philip S. Hench Distinguished Alumnus Award, Univ. of Pittsburgh School of Medicine
2013 Women in Ophthalmology Scientific Honorary Award and Lecture, Snowmass, CO
2013 Women in Ophthalmology and American Medical Association Mentoring Award
2014 Kreissig Award from Euretina, the European Macula, Retina, Vitreous Society
2017 Mildred Weisenfeld Award, ARVO
2017 Fight for Sight Award, ARVO
2017 Lucien Howe Medal Award

Publications + National Presentations

1.Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E and advanced age-related macular degeneration. A multicenter study. JAMA 1994; 272:1413-1420. (Seddon JM was principal investigator of this study, designed the diet questionnaire and analyzed the data.)

2. Seddon JM, Willett WC, Speizer FE, Hankinson SE. A prospective study of cigarette smoking and age-related macular degeneration in women. JAMA 1996; 276:1141-1146. (Seddon JM initiated the eye component of the study and wrote the grant.)

3. Seddon JM, Cote J, Davis N, Rosner B. Progression of age-related macular degeneration: Association with dietary fat, transunsaturated fat, nuts, and fish intake. Arch Ophthalmol 2003; 121:1728-1737. (Seddon JM enrolled patients from her clinic population, designed the study and forms, collected the data, and supervised the analyses.)

4. Seddon JM, Cote J, Page W, Aggen SH, Neale MC. The U.S. age-related macular degeneration twin study: relative roles of genetic and environmental influences. Arch Ophthalmol 2005; 123:323-327.

5. Raychaudhuri S, Iartchouk O, Chin K, Tan PL, Tai A, Ripke S, Gowrisankar S, Vemuri S, Montgomery K, Yu Y, Reynolds R, Zack DJ, Campochiaro B, Campochiaro P, Katsanis N, Daly MJ, Seddon JM. A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. Nature Genetics 2011; 43(12):1232-36.

6. Seddon JM, Yu Y, Miller EC, Reynolds R, Tan PL, Gowrisankar S, Goldstein JI, Triebwasser M, Anderson HE, Zerbib J, Kavanagh D, Souied E, Katsanis N, Daly MJ, Atkinson JP, Raychaudhuri S. Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. Nat Genet 2013; 45:1366-1370.

7. Sobrin L, Seddon JM. Nature and Nurture-Genes and Environment-Predict Onset and Progression of Macular Degeneration. Prog Ret Eye Res 2014; 40:1-15.

8. Merle BM, Silver RE, Rosner B, Seddon JM. Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study. Am J Clin Nutr 2015; 102(5):1196-206.

9. Wagner EK, Raychaudhuri S, Villalonga MB, Java A, Triebwasser MP, Daly MJ, Atkinson JP, Seddon JM. Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD. Sci Reports 2016; 6:31531. doi: 10.1038/srep31531.

10. Ferrara D, Silver RE, Louzada RN, Novais EA, Collins GK, Seddon JM. Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci 2017; 58:3519-3529. ffiliates; Winchester Hospital and Melrose Wakefield Hospital in Melrose, MA.

1. Thompson JT, Seddon JM. Eat Right For Your Sight: Simple, Tasty Recipes That Help Reduce the Risk of Vision Loss from Macular Degeneration. American Macular Degeneration Foundation. The Experiment, LLC. New York, NY; 2015.


Johanna Seddon, MD, ScM, is a leading international expert in the causes and treatment of Age-related Macular Degeneration (AMD), the leading cause of blindness in people over age 65. She is Founding Director of the Ophthalmic Epidemiology and Genetics Service at Tufts Medical Center and Professor of Ophthalomogy at Tufts University School of Medicine.

She is a member of the Scientific Advisory Board for the Foundation Fighting Blindness. Dr. Seddon is board certified in Ophthalmology, and her clinical specialties include vitreoretinal diseases, macular dystrophies, hereditary retinal disorders and retinal vascular disorders.

Professional Memberships

American Society of Retina Specialists