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Lesley A. Inker, MD, MS
Director, Kidney and Blood Pressure Center; Director, Kidney Function and Evaluation Center; Director, Quality Improvement; Associate Professor, Tufts University School of Medicine
Department + Services
Clinical Focus Areas
Geriatric nephrology, pregnancy, HIV-associated kidney disease, kidney transplantation, kidney donor evaluation, medical treatment for kidney failure without dialysis, kidney function evaluation (GFR), general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones
Seeing Patients In
|Programs + Specialties
|Training + Education
McMaster School of Medicine, Hamilton, Ontario; McMaster University Hospitals; University of British Columbia, Vancouver; Tufts Medical Center
||Internal Medicine, Nephrology
||View Accepted Insurances at Tufts MC + Floating Hospital
Tufts Medical Center
35 Kneeland St.
Boston, MA 02111
Phone #: 617-636-5866
Fax #: 617-636-2369
2018, "Top Doctor," Boston Magazine
2018, Garabed Eknoyan Award from National Kidney Foundation
2017, "Top Doctor," Boston Magazine
2000, Second and Third Prizes in Oral Presentation Category, Annual Resident Research Day, McMaster University
1999, Best Oral Presentation, South-West Ontario Critical Care Conference, London Ontario
1998, First Prize in Case Report Category, Annual Res
View a full list of Dr. Inker's publications here.
Dr. Inker's clinical interests are general nephrology, detection and treatment of CKD, assessment of kidney function, geriatric nephrology, HIV-associated kidney disease, and kidney stones. She is the Director for Quality Improvement for the Division, Director of the Kidney and Blood Pressure Center and director of the Kidney Function Evaluation Clinic
Dr. Inker’s primary research interests are in epidemiology and outcomes related to CKD. Her major research interest is in the estimation ad measurement of glomerular filtration rate (GFR). She was the co-principal investigator of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), a collaborative effort to use pooled individual patient data to address central questions in the epidemiology of CKD, including developing improved glomerular filtration rate (GFR) estimation equations, using these equations to refine prevalence estimates for CKD from National Health and Nutrition Examination Survey. The principle outcomes of this work are new estimating equations for GFR the CKD-EPI creatinine equation, the CKD-EPI cysatin C equation and the CKD-EPI creatinine-cystatin C equation. All of these are more accurate than the currently most commonly used equation, the MDRD Study equation. The creatinine-cystatin C equation is more precise than either the CKD-EPI creatinine or the CKD-EPI cystatin C equation. More recently, she is investigating novel filtration markers, including low molecular weight proteins, beta trace protein and beta-2-microglobulin. dR Inker has led or collaborated in several research studies to evaluate kidney function in other populations, including HIV positive people, elderly, patients with severe liver disease and cancer. She is now an investigator in the NIDDK CKD-Biomarker Consortium, a collaborative effort to discover and validate new markers for CKD.
Another major research interest is investigation of alternative endpoints for kidney disease outcomes in clinical trials, including changes in urine protein and lesser declines in GFR compared to the currently accepted doubling of serum creatinine.
Policy - Guideline Development and Implementation
Dr. Inker is also interested in research and policy related to implementation of CKD Guidelines. She works with NKF leadership and national organizations to implement CKD guidelines, including issues related to GFR estimation and revisions to diagnostic codes for kidney disease.
Chair, Steering Committee NKF Patient Network
Alport Syndrome Foundation Medical Advisory Council
National Kidney Foundation
Clinical Oversight committee, co-chair, Kidney Early Education Program (KEEP)
International Renal Work Group for revisions to the International Classification of Disease - 11th edition. Co-chair
Member, scientific advisory board, National Kidney Foundation
Member, National Kidney Disease Education Program