Molecular Cardiology Research Institute (MCRI)

Drug Screening + Fly Lab

The MCRI Drosophila laboratory utilizes the fruit fly to expedite the characterization of genes relevant to human skeletal muscle/cardiac physiology and disease. The laboratory uses a broad array of complementary genetic, molecular, pharmacological and behavioral approaches applicable to the Drosophila model organism. MCRI fly models of muscular dystrophies and heart disease are generated and integrated in research pipelines established at TMC and other research institutions. These pipelines include invertebrate and vertebrate model organisms, and human cell lines, to facilitate the discovery of novel drug targets and/or candidate therapeutics.