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Molecular Cardiology Research Institute (MCRI)

Center for Translational Pharmacology and Genomics

The Center for Translational Pharmacology and Genomics includes investigators whose core interest’s center on leveraging molecular pharmacology, biology and genetic approaches toward the development of novel therapeutics. Ongoing studies have clinical application in cardiovascular, inflammatory, metabolic and skeletal muscle disease. Work performed by the Center laboratories includes (i) state of the art genomic approaches (e.g. ChIP-seq, RNA-seq, RNAi), (ii) generation and analysis of invertebrate (Drosophila) and vertebrate animal models of human diseases, (iii) structure-function studies on a wide variety of pharmacological targets (receptors, channels, enzymes) and (iv) development of novel tools enabling peptide and small molecule drug discovery. The wide array of research capabilities featured by the Center laboratories naturally extends beyond the boundaries of one organ system or pathway offering the unique ability to understand many complex and/or inherited chronic diseases.

The Center Investigators hold faculty positions in the Tufts University School of Medicine graduate programs and regularly mentor Masters, PhD-level thesis students and Post-Doctoral Fellows in Pharmacology, Genetics, Clinical Translational Sciences and Cell, Molecular and Developmental Biology.

Gordon Huggins, MD is a cardiologist at Tufts Medical Center.Gordon Huggins

  

 


 

 

 

 


Dr. Beinborn is a researcher in the Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center in downtown Boston, MA.Martin Beinborn

 

 

 

  

 


 


Dr. Michael ChinMichael Chin

 

 

 

 

 

 


Isabelle Draper is a researcher in the Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center in downtown Boston, MA.Isabelle Draper

 

 

 

 

 

 


Dr. Kopin is a researcher in the Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center in downtown Boston, MA.Alan Kopin