The Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center in downtown Boston, MA studies the molecular mechanisms of cardiovascular disease and translates basic findings into new clinical strategies for diagnosis and therapy. Our mission also emphasizes mentoring MD and PhD trainees committed to careers in academic cardiovascular research.
Improving Cardiovascular Health through Groundbreaking Research
MCRI applies advanced molecular methods to understanding mechanisms important in human biology and disease. The ultimate goal of MCRI researchers is to translate basic findings into new clinical strategies for diagnosis and therapy, with a focus on small molecule drug discovery, gene therapy approaches and molecular predictive strategies.
Ongoing molecular vascular biology studies are being expanded to include further investigations of ischemic cardiovascular diseases such as angina and myocardial infarction, as well as other major cardiovascular disorders, especially hypertension, congestive heart failure and disorders of cardiac electrophysiology.
Continually Investing in People, Discovery and Technology
To fulfill our objectives of conducting basic research for translation into new diagnostics and therapies and educating the next generation of cardiovascular researchers, MCRI has invested in four principal areas:
Research Focus Areas
The MCRI programmatic areas of focus include vascular biology, cardiomyocyte biology, electrophysiology, human genetics and genomics, molecular pharmacology, and signal transduction. Members of the MCRI work closely and collaboratively with clinical cardiologists and cardiovascular surgeons, biochemists, neuroscientists, pharmacologists, geneticists and epidemiologists at Tufts Medical Center and Tufts University to further research in all facets of cardiovascular diseases.