Mother Infant Research Institute (MIRI)
The research performed by the principal investigators of the Mother Infant Research Institute (MIRI) at Tufts Medical Center and Floating Hospital for Children covers a wide range of approaches, including:
- Basic science research (e.g. using cells in culture or model animal systems)
- Translational research (e.g. applying state-of-the-art molecular techniques to human material such as blood or saliva samples)
- Clinical research that involves direct “hands-on” interaction with a pregnant woman or her newborn infant
Multiple Labs Dedicated to Mother Infant Research
Although in some cases the investigator works with patients at the bedside and not in a laboratory, for the sake of consistency we describe each group as a laboratory.
The MIRI laboratories include:
- The Bianchi Laboratory focuses on reproductive genomic medicine, prenatal diagnosis, fetal treatment, fetal cell microchimerism and regenerative medicine.
- The Edlow Laboratory focuses its research efforts on maternal obesity and its impact on fetal gene expression and neurodevelopment.
- The House Laboratory uses a bioengineering strategy to investigate cervical biomechanics, specifically cervical function, as it relates to the cause of spontaneous premature birth.
- The Maron Laboratory studies saliva from premature newborns and its wealth of information about many of newborns’ developing systems, such as the gastrointestinal tract and the brain.
- The Norwitz Laboratory has a number of complementary research initiatives focused on a single overall objective: to improve the ability of obstetric care providers to predict and prevent preterm birth.
- The Tarui Laboratory focuses on better defining the long-term prognosis and developing new therapies for fetuses that are diagnosed with brain malformations, leading to more accurate prenatal counseling to expectant couples.
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