Back to Results


Title Maternal Metabolic Mediators of infant Adiposity (MaMMA)
Therapeutic Area Pregnancy
Principal Investigator Perrie O'Tierney-Ginn
Min Age 18 Years
Max Age 45 Years
Gender Female
Contact Taysir Mahmoud


The purpose of this study is to measure the effect of maternal diet and metabolism (how your body uses food for energy) on the growth of the baby, and how the placenta uses lipids.

Study Details

Inclusion Criteria

  • GA > 8 weeks - <16 weeks.
  • Planning to deliver at Tufts Medical Center
  • Able to comply with consuming study-provided prenatal vitamins

Exclusion Criteria

  • History of gestational diabetes, hypertension, pre-term birth or small-for gestational age in prior pregnancy.
  • Multiple gestation (ie. twins, triplets).
  • Maternal smoking during current pregnancy

Study Requirements

Participants will have two 1/2 day study visits in early pregnancy (12-16 weeks gestation), and two in late pregnancy (34-36 weeks) at the Human Nutrition Research Center to measure maternal body composition, diet and metabolism. About 3 tablespoons of blood will be drawn at each visit. After delivery, the placenta will be collected, and baby measurements of growth will be performed.