Men with severe symptoms of bladder outlet obstruction often have associated bladder fibrosis leading to diminished bladder contractility. Planning to perform a pilot study using 10 urine samples from controls without urinary symptoms and from 10 men with severe urinary symptoms as noted on the International Prostate Symptom Score (IPSS) questionnaire. Assays will determine levels of collagen within the urine samples from both groups.
- Ages 50-80
- Men with severe symptoms of bladder outlet obstruction
- Men who have undergone surgery for bladder outlet obstruction
20 men will submit urine samples in the urology clinic.