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Collagen Urine Assay


Title A Novel Urine assay to determine collagen levels in men with severe symptoms of bladder outlet obstruction
Therapeutic Area Urine and Urination, Bladder Diseases
Principal Investigator Richard Caesar, MD
Min Age 50 Years
Max Age 80 Years
Gender Male
Contact Richard Caesar, MD
617-636-6317
RCaesar@tuftsmedicalcenter.org

Overview

Men with severe symptoms of bladder outlet obstruction often have associated bladder fibrosis leading to diminished bladder contractility. Planning to perform a pilot study using 10 urine samples from controls without urinary symptoms and from 10 men with severe urinary symptoms as noted on the International Prostate Symptom Score (IPSS) questionnaire. Assays will determine levels of collagen within the urine samples from both groups.

Study Details

Inclusion Criteria

  • Male
  • Ages 50-80
  • Men with severe symptoms of bladder outlet obstruction

Exclusion Criteria

  • Female
  • Children
  • Men who have undergone surgery for bladder outlet obstruction

Study Requirements

20 men will submit urine samples in the urology clinic.