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This phase II/III trial compares the side effects and activity of oral azacitidine in combination with the standard drug therapy (reduced dose rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone [R-miniCHOP]) versus R-miniCHOP alone in treating patients 75 years or older with newly diagnosed diffuse large B cell lymphoma. R-miniCHOP includes a monoclonal antibody (a type of protein), called rituximab, which attaches to the lymphoma cells and may help the immune system kill these cells.

Announcements
September 18, 2020
In the 2020 US News & World Report Best Hospital Rankings, Lowell General Hospital was ranked 7th best in the Greater Boston region and the top community hospital in the area.
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Since January 2018, the CardioVascular Center has published numerous reports in peer-reviewed journals. These are the highlighted high-impact manuscripts from this quarter.
Articles
August 27, 2021
Dr. Adam Weston, an infectious disease specialist at Lowell General Hospital and a clinical leader in the hospitals’ pandemic response discusses the latest updates on 3rd dose and booster shots as well as the outlook for COVID-19 this fall.
Articles
June 21, 2019
Learn about the Gamma Knife radiosurgery technology, used by Tufts MC neurosurgeons in Boston to treat brain and facial conditions without an incision.
Announcements
June 30, 2021
Dr. Geetanjali Akerkar, a Circle Health gastroenterologist, was selected as the Middlesex North District Medical Society’s 2021 Community Clinician of the Year, an award that recognizes her professionalism and contributions as a physician.
clinical trial
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Utilize fresh tumor tissue to aid the development of future therapies for brain cancer.

Briefly, a cell immunotherapy consisting of a patient’s autologous glioblastoma tumor cells, called ‘IGV-001’, is being tested in clinical trials. In order to advance clinical and product development of IGV-001, Imvax is seeking access to patient material to test key product parameters in a laboratory setting.

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