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Acromegaly

Acromegaly is a hormone disorder that occurs when the pituitary gland produces too much growth hormone (GH) in the body.

Occasionally, pituitary disorders may not require intensive medical or surgical treatments but instead, can be monitored through careful observation to ensure that they do not become larger problems.

Most patients with diseases affecting the pituitary gland require careful ophthalmic follow-up because of the proximity of the visual apparatus. The result of pituitary disease may be loss of peripheral vision, which may not always be apparent to the patient. Also, pituitary diseases (especially tumors in this area) can affect the ocular motor nerves causing double vision.

The hormonal disorder acromegaly results from excess growth hormone production from a pituitary tumor. These patients may experience profound and even disfiguring effects. Gigantism is seen in children and adolescents with too much growth hormone (the largest giant on record was 8’ 11” tall). In adults, it leads to increased tissue growth, organ enlargement, and disfigured facial features—large nose, lips, jaw, tongue; deeply furrowed forehead; increased spacing between teeth -, large hands and feet, increased sweating, in addition to a variety of systemic effects that affect blood pressure, blood fats and carbohydrate metabolism (potentially causing diabetes), and may be associated with an increased risk of cancer.

Programs + Services


Neuroendocrine and Endocrine Neoplasia Clinic

The Neuroendocrine and Endocrine Neoplasia Clinic at Tufts Medical Center in Boston provides care for patients with hypothalamic, suprasellar and pituitary disorders.
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Neuroendocrine and Pituitary Program

The Neuroendocrine and Pituitary Program at Tufts Medical Center in Boston cares for patients with hypothalamic, suprasellar and pituitary disorders, like pituitary adenomas.
More information about programs and services

Doctors + Care Team

Carl B. Heilman, MD

Carl B. Heilman, MD

Title(s): Neurosurgeon-in-Chief; Chairman of Neurosurgery; Professor, Tufts University School of Medicine
Department(s): Neurosurgery
Appt. Phone: 617-636-5860
Fax #: 617-636-7587

Meningiomas, acoustic neuromas, skull base surgery, pituitary surgery, Chiari surgery

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Ronald M. Lechan, MD, PhD
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Ronald M. Lechan, MD, PhD

Title(s): Chief, Division of Endocrinology, Diabetes and Metabolism; Director, Hypothalamic and Pituitary Disease Center; Professor, Tufts University School of Medicine
Department(s): Medicine, Endocrinology, Diabetes and Metabolism
Appt. Phone: 617-636-5689
Fax #: 617-636-4719

Hypothalamic disease, pituitary disease, disorders of the thyroid, adrenal disease, islet cell tumors

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Adel M. Malek, MD, PhD

Adel M. Malek, MD, PhD

Title(s): Chief, Division of Neurovascular Surgery; Professor, Tufts University School of Medicine
Department(s): Neurosurgery
Appt. Phone: 617-636-8200
Fax #: 617-636-7587

Aneurysms, arteriovenous malformations, dural fistulas, subarachnoid hemorrhage, intracranial atherosclerosis, arterial dissection

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James Kryzanski, MD

James Kryzanski, MD

Title(s): Chief, Division of Epilepsy Surgery; Co-Chief, Division of Spinal Surgery; Assistant Professor, Tufts University School of Medicine
Department(s): Neurosurgery
Appt. Phone: 617-636-8585
Fax #: 617-636-7587

Epilepsy neurosurgery, skull base surgery, pituitary surgery, neurovascular surgery, minimally invasive spine surgery, neurosurgical disorders in patients with achondroplasia, neurosurgical disorders in patients with Down syndrome

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John E. Mignano, MD, PhD

John E. Mignano, MD, PhD

Title(s): Radiation Oncologist; Clinic Director; Associate Professor, Tufts University School of Medicine
Department(s): Radiation Oncology, Pediatric Radiation Oncology
Appt. Phone: 617-636-6161
Fax #: 617-636-4513

Oncologic consultation for general radiotherapy and Gamma Knife, pediatric radiation oncology

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Julian K. Wu, MD

Julian K. Wu, MD

Title(s): Associate Chairman, Department of Neurosurgery; Chief, Division of Neurosurgical Oncology; Neurosurgery Residency Program Director; Professor, Tufts University School of Medicine
Department(s): Neurosurgery
Appt. Phone: 617-636-4500
Fax #: 617-636-7587

Neuro-oncology, Gamma Knife radiosurgery, meningiomas, pituitary tumors, gliomas, brain metastasis, trigeminal neuralgia

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Thomas R. Hedges III, MD

Thomas R. Hedges III, MD

Title(s): Director, Neuro-Ophthalmology Service; Co-Director, Electrophysiology Service; Director, Neuro-Ophthalmology Fellowship Program; Professor, Tufts University School of Medicine
Department(s): Ophthalmology
Appt. Phone: 617-636-5488
Fax #: 617-636-7029

Neuro-ophthalmology

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