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Ankylosing Spondylitis

Ankylosing spondylitis is a type of spinal arthritis that causes swelling between the discs that make up the spine.

Doctors + Care Team

Timothy E. McAlindon, MD, MPH

Timothy E. McAlindon, MD, MPH

Title(s): Chief, Division of Rheumatology; Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

Osteoarthritis, general rheumatology, lupus

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Janeth Yinh, MD

Janeth Yinh, MD

Title(s): Rheumatologist; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, musculoskeletal ultrasound

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Robert A. Kalish, MD

Robert A. Kalish, MD

Title(s): Director, Rheumatology Education; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, Lyme disease

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Senada Arabelovic, DO

Senada Arabelovic, DO

Title(s): Rheumatologist; Assistant Professor of Medicine, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, transitioning young adults with autoimmune diseases to the adult rheumatology clinic, pregnancy in rheumatologic disease

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Steven C. Vlad, MD, PhD

Steven C. Vlad, MD, PhD

Title(s): Rheumatologist; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, spondyloarthopathies, psoriatic arthritis and anklylosing spondylitis

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William F. Harvey, MD, MSc, FACR

William F. Harvey, MD, MSc, FACR

Title(s): Rheumatologist; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

Osteoarthritis, general rheumatology, Musculoskeletal Ultrasound

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Research + Clinical Trials


A Multicenter, Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study To Evaluate The Efficacy And Safety Of Bimekizumab In Subjects With Active Ankylosing Spondylitis

BE AGILE 1 is evaluating a new drug called bimekizumab for patients with Ankylosing spondylitis. Bimekizumab is investigational, which means it is still being tested and has not yet been approved for treatment by health authorities. Bimekizumab may help lower the level of activity of interleukin-17A (IL-A) and interleukin-17F (IL-17F); two proteins that are involved in an inflammatory response believed to cause the symptoms of anklysing spondylitis. The purpose of this study is to help us understand how safe and effective different doses of bimekizumab are in treating your condition. It will also help us understand how bimekizumab acts in your body, and how your body reacts to bimekizumab.
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