Clostridium Difficile Infection
Clostridium difficile is a bacterium that causes diarrhea and more serious intestinal conditions such as colitis.
Programs + Services
The Infectious Disease Clinic provides care to patients for a wide range of conditions from our general clinic and several comprehensive subspecialty clinics.
More information about programs and services
Doctors + Care Team
Title(s): Attending Physician, Division of Geographic Medicine and Infectious Diseases; Faculty, Tufts Center for Integrated Management of Antimicrobial Resistance (CIMAR); Dean and Professor of Medicine, Tufts University School of Medicine
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-7010
Fax #: 617-636-8525
Care of immunocompromised patients, transplant-related infections and S. aureus/MRSA infections
View Full Profile for Helen W. Boucher, MD, FACP, FIDSA
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Accepting New Patients
LGBTQ+ Health
Virtual Appointments Available
Title(s): Attending Physician; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-7010
Fax #: 617-636-8525
HIV/AIDS, PrEP, human papilloma virus and anal dysplasia, sexually transmitted infections, general infectious diseases
View Full Profile for Jose A. Caro, MD
Accepting New Patients
Virtual Appointments Available
Title(s): Attending Physician; Associate Professor of Medicine, Tufts University School of Medicine
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-7010
Fax #: 617-636-7100
General infectious diseases, C. difficile, infections in immunocompromised hosts, infections in returning travelers
View Full Profile for Yoav Golan, MD, MS, FIDSA
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Accepting New Patients
Title(s): Attending Physician
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-7010
Fax #: 617-636-7100
Infectious diseases, HIV/AIDS, travel medicine, HIV/HCV co-infection
View Full Profile for James Hellinger, MD, MSc
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Accepting New Patients
LGBTQ+ Health
Virtual Appointments Available
Title(s): Director, Infectious Diseases Clinic; Director, Traveler's Health Service; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-7010
Fax #: 617-636-7100
HIV, pre-exposure prophylaxis for HIV, post-exposure prophylaxis for blood-borne pathogens, traveler's health and tropical medicine, general infectious diseases
View Full Profile for Laura Kogelman, MD
Accepting New Patients
Virtual Appointments Available
Title(s): Medical Director, Inpatient Wound Prevention and Management; Attending Physician; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-7761
Fax #: 617-636-3198
Transplant infectious diseases, wound care at the Center for Vascular Medicine, Wound Healing & Hyperbaric Medicine, travel medicine, general infectious disease
View Full Profile for Natalie E. Nierenberg, MD, MPH
Title(s): Emeritus Chief, Division of Geographic Medicine and Infectious Diseases; Emeritus Hospital Epidemiologist; Vice Chair for Research Department of Medicine; Professor, Tufts University School of Medicine
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-5788
Fax #: 617-636-8525
General infectious diseases, cytomegaloviruses and transplantation infectious diseases
View Full Profile for David R. Snydman, MD, FACP, FIDSA, FAST
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Accepting New Patients
Virtual Appointments Available
Title(s): Attending Physician; Co-Director of the Mycobacteria Treatment Clinic; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Geographic Medicine and Infectious Diseases
Appt. Phone: 617-636-7010
Fax #: 617-636-7100
HIV treatment, tuberculosis and atypical mycobacteria care
View Full Profile for David R. Stone, MD
Research + Clinical Trials
ECOSPOR Ill is a Phase 3, multicenter, randomized, double-blind, placebo- controlled, parallel-group study of the safety, tolerability, and efficacy of SER-109 versus placebo in adult subjects 18 years of age or older with recurrent CDI, defined as: a history of;:: 3 CDI episodes within 12 months, inclusive of the current episode. This study is designed to demonstrate the superiority of SER-109 versus placebo to reduce recurrence of Clostridium difficile infection (CDI) in adults who have received antibacterial drug treatment for recurrent CDI (RCDI), based on the proportion of subjects experiencing a CDI recurrence requiring antibiotic treatment up to 8 weeks after initiation of treatment.
More information about research and clinical trials
ECOSPOR IV is an open-label extension of Study SERES-012. This study is designed to evaluate the safety, tolerability, and efficacy of a SER-109 treatment regimen in adult subjects 18 years of age or older with recurrent Clostridium difficile infection (RCDI), who received a SER-109 or placebo treatment regimen in Study SERES-012.
More information about research and clinical trials
