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Epilepsy is a brain disorder that causes people to have recurring seizures. The seizures happen when clusters of nerve cells, or neurons, in the brain send out the wrong signals. People may have strange sensations and emotions or behave strangely. They may have violent muscle spasms or lose consciousness.

Doctors + Care Team

James Kryzanski, MD

James Kryzanski, MD

Title(s): Chief, Division of Epilepsy Surgery; Co-Chief, Division of Spine Surgery; Assistant Professor, Tufts University School of Medicine
Department(s): Neurosurgery
Appt. Phone: 617-636-8585
Fax #: 617-636-7587

Epilepsy neurosurgery, skull base surgery, pituitary surgery, neurovascular surgery, minimally invasive spine surgery, neurosurgical disorders in patients with achondroplasia, neurosurgical disorders in patients with Down syndrome

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Joel Oster, MD

Joel Oster, MD

Title(s): Director, Level 4 Epilepsy Center; Neurologist
Department(s): Neurology
Appt. Phone: 617-636-5848
Fax #: 617-636-8199

Epilepsy, intractable epilepsy, detection of difficult to find possible lesions causing epilepsy, structural and metabolic brain imaging, clinical drug trials for seizure disorders, general neurology, sleep disorders, neurologic/epilepsy intensive monitoring, intraoperative neurophysiologic monitoring

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Ju Tang, MD, PhD

Ju Tang, MD, PhD

Title(s): Director, Pediatric Epilepsy Program and Pediatric EEG Laboratory; Pediatric Neurologist; Epileptologist; Assistant Professor, Tufts University School of Medicine
Department(s): Pediatrics, Pediatric Neurology
Appt. Phone: 617-636-8100
Fax #: 617-636-8375

Epilepsy, pediatric neurology

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Research + Clinical Trials

Cognitive Debriefing and Usability Testing of an Epilepsy Seizure Diary

Evaluation of a seizure diary.
More information about research and clinical trials

A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study Exploring the Efficacy, Safety, and Tolerability of Natalizumab (BG00002) as Adjunctive Therapy in Adult Subjects With Drug-Resistant Focal Epilepsy

This is a 6-month randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of natalizumab as adjunctive therapy in the treatment of adult subjects with drug-resistant focal epilepsy. The primary efficacy objective of the study is to determine if adjunctive therapy of natalizumab 300mg intravenous (IV) every 4 weeks reduces the frequency of seizures in adult participants with drug-resistant focal epilepsy. The secondary efficacy objective is to assess the effects of natalizumab versus placebo in drug-resistant focal epilepsy on additional measures of seizure frequency. 
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