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High Blood Pressure

High blood pressure (hypertension) is an increase in the force of blood against the arteries in the body. A blood pressure reading of 140/90 or higher indicates high blood pressure.

Programs + Services


Clinical Nutrition

The Division of Clinical Nutrition at Tufts Medical Center provides inpatient and outpatient nutritional services.
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Preventive Cardiology Center

Explore the Preventive Cardiology Center at Tufts Medical Center in downtown Boston which specializes in cardiovascular disease prevention and treatment.
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Women's Heart Center

Discover The Women’s Heart Clinic at Tufts Medical Center and learn more about the cardiologists dedicated to providing women with the best heart care.
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Doctors + Care Team

Iris Z. Jaffe, MD, PhD

Iris Z. Jaffe, MD, PhD

Title(s): Executive Director, Molecular Cardiology Research Institute (MCRI); Cardiologist; Director, Vascular Biology Research Center within the MCRI; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, CardioVascular Center, Cardiology
Appt. Phone: 617-636-9370
Fax #: 617-636-1444

General cardiology, resistant hypertension

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Edward Saltzman, MD

Edward Saltzman, MD

Title(s): Chief, Division of Clinical Nutrition; Director, Adult Nutrition Support Services; Associate Professor, Tufts University School of Medicine; Dean for Education, Friedman School of Nutrition Science and Policy, Tufts University
Department(s): Medicine, Clinical Nutrition
Appt. Phone:
Fax #:

Enteral and parenteral nutrition

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Andrew S. Greenberg, MD

Andrew S. Greenberg, MD

Title(s): Endocrinologist; Dr. Robert and Veronica Atkins Professor in Metabolism and Nutrition, Tufts University School of Medicine
Department(s): Medicine, Clinical Nutrition, Endocrinology, Diabetes and Metabolism
Appt. Phone: 617-556-3144
Fax #: 617-556-3224

Obesity, lipid disorders, diabetes, general endocrinology

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Ayan R. Patel, MD

Ayan R. Patel, MD

Title(s): Director, Cardiovascular Imaging and Hemodynamic Laboratory; Director, Women's Heart Center; Professor, Tufts University School of Medicine
Department(s): Medicine, CardioVascular Center, Cardiology
Appt. Phone: 617-636-2273
Fax #: 617-636-8070

Echocardiography, heart failure, women's heart disease

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Gordon S. Huggins, MD

Gordon S. Huggins, MD

Title(s): Investigator, Molecular Cardiology Research Institute (MCRI) Center for Translational Genomics; Cardiologist, Preventive Cardiology Center; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, CardioVascular Center, Cardiology
Appt. Phone: 617-636-2273
Fax #: 617-636-5649

Cardiology, preventive cardiology

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Joel B. Mason, MD

Joel B. Mason, MD

Title(s): Gastroenterologist; Professor, Tufts University Schools of Medicine and Friedman School of Nutritional Science and Policy; Senior Scientist and Director, Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
Department(s): Medicine, Clinical Nutrition, Gastroenterology
Appt. Phone: 617-636-5883
Fax #: 617-636-1480

Nutritional aspects of gastrointestinal disease, home nutritional therapy, enteral and parenteral nutrition, nutrition and cancer prevention

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Jonas B. Galper, MD, PhD

Jonas B. Galper, MD, PhD

Title(s): Director, Laboratory of Lipid Metabolism and CardioVascular Signaling, Molecular Cardiology Research Institute; Professor, Tufts University School of Medicine
Department(s): Medicine, CardioVascular Center, Cardiology
Appt. Phone: 617-636-2273
Fax #: 617-636-4833

General cardiology, molecular mechanisms of cardiovascular diseases

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Research + Clinical Trials


Renal Denervation Using the Vessix Renal Denervation System for the Treatment of Hypertension

The REDUCE HTN: REINFORCE study is testing a new procedure that could treat high blood pressure.  This procedure is called renal (kidney) denervation.  The study will be evaluating patients that have high blood pressure when they do not take medications. The study will compare the blood pressure of people who undergo the study procedure (renal denervation) with the blood pressure of those who undergo a sham procedure (a renal angiogram that will not include the renal denervation). The study’s purpose is to collect data about the safety and effectiveness of this renal denervation (disabling of kidney nerves) treatment for patients with uncontrolled hypertension.

The Vessix™ Renal Denervation System consists of a catheter (a thin tube) and a radio frequency (RF) generator (power generator).  The procedure involves the nerves that surround the blood vessel (artery) that supplies blood to the kidney (kidney artery). The generator sends energy through the kidney artery to disable the surrounding nerves. These nerves have a role in causing the kidneys to keep sodium (salt) in the body and in causing the amount of blood flowing into the filters in the kidney to be lower. These two things, among others, can then cause high blood pressure.  By disabling these nerves, the Vessix system aims to reduce the amount of salt kept in the body and therefore reduce blood pressure in the body.

Renal denervation is not a treatment currently used for high blood pressure management in the U.S.  The device is investigational in the United States. It is not approved by the U.S. FDA. The sponsor of this study is Boston Scientific Corporation.  

The study will include 100 subjects at up to 20 hospitals in the US (about 20 of these subjects will be enrolled at Tufts Medical Center). About 67 people of the 100 total will get the renal denervation procedure (study group) and about 33 people will get a “sham” procedure (control group). People will be randomly selected to one or the other group.  The doctor doing the procedure will know which group you are in when he is doing the procedure. Your Study Doctor will tell you whether you received the renal denervation procedure or the sham procedure at your 6 month follow-up visit. Until then, neither you nor your Study Doctor will know which procedure you received. The sham procedure is done to get data that is not influenced by knowing what procedure you received.
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Tufts Medical Center and Floating Hospital for Children have high quality care.

Quality + Safety

A world-class teaching hospital shouldn’t make you feel small.  At Tufts Medical Center the patient is at the center of everything that we do.  This means we’re committed to providing the highest quality of care in a safe, friendly environment.

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The City of Boston.

200 Years of Caring for the Community

Tufts Medical Center has been taking care of Boston and the surrounding community for more than 200 years.

Read about our enduring history