Kidney Failure

The two kidneys filter blood, take out waste, and make urine. With kidney failure, a treatment is needed to replace the work the kidneys normally do. The treatment options are dialysis or a kidney transplant. 

Programs + Services


Clinical Nutrition

The Division of Clinical Nutrition at Tufts Medical Center provides inpatient and outpatient nutritional services.
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Outpatient Dialysis Clinic

The Tufts Medical Center Outpatient Dialysis Clinic provides comprehensive in-center and home dialysis services for patients experiencing kidney failure.
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Kidney and Blood Pressure Center

The Tufts MC Kidney and Blood Pressure Center provides both one-time consultations and ongoing care for chronic or acute kidney disease and high blood pressure.
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Kidney Transplantation

The Division of Transplant Surgery at Tufts Medical Center specializes in kidney transplants, having preformed them for over 40 years.
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Doctors + Care Team

Ronald D. Perrone, MD

Ronald D. Perrone, MD

Accepting New Patients

Title(s): Scientific Director, Clinical and Translational Research Center; Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology, Clinical and Translational Research Center (CTRC)
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Polycystic kidney disease (PKD)

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Mark J. Sarnak, MD, MS

Mark J. Sarnak, MD, MS

Accepting New Patients

Title(s): Chief, Division of Nephrology; Director, Research Training Program; Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Dialysis, general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Alin Annie Joseph, MD, MS

Alin Annie Joseph, MD, MS

Accepting New Patients

Title(s): Nephrologist; Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 978-287-4788
Fax #: 978-287-5126

General nephrology, transplant nephrology, glomerulonephritis

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Amy Kuhlik, MD

Amy Kuhlik, MD

Accepting New Patients

Title(s): Nephrologist; Dean for Student Affairs and Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Pregnancy, general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Andrew S. Levey, MD

Andrew S. Levey, MD

Title(s): Chief Emeritus, Division of Nephrology; Professor of Medicine, Tufts University School of Medicine; Dr. Gerald J and Dorothy R. Friedman Professor Emeritus, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Kidney function evaluation (GFR), chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, systemic lupus erythematosus, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Dana C. Miskulin, MD, MS

Dana C. Miskulin, MD, MS

Accepting New Patients

Title(s): Nephrologist; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Polycystic kidney disease (PKD), dialysis, home dialysis, general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Daniel E. Weiner, MD, MS

Daniel E. Weiner, MD, MS

Accepting New Patients

Title(s): Nephrologist; Associate Medical Director, Dialysis Clinic, Inc., Boston; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Dialysis, hypertension, general nephrology, chronic kidney disease (CKD), diabetic kidney disease, conservative kidney care, cardiovascular disease in patients with kidney disease, and acute kidney disease

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David Drew, MD, MS

David Drew, MD, MS

Accepting New Patients

Title(s): Nephrologist; Assistant Professor of Medicine, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

General nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury, kidney stones and monoclonal gammopathy of renal significance

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Jeffrey Cooper, MD

Jeffrey Cooper, MD

Accepting New Patients

Title(s): Chief, Transplant Surgery; Transplant Surgeon; Director, General Surgery Residency Program; Associate Professor, Tufts University School of Medicine
Department(s): Surgery, Transplant Surgery
Appt. Phone: 617-636-5592
Fax #: 617-636-8228

Liver, kidney and pancreas transplantation

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Klemens B. Meyer, MD

Klemens B. Meyer, MD

Accepting New Patients

Title(s): Medical Director, Dialysis Clinic, Inc., Boston and Walden Pond, Concord, MA; Director Dialysis Services, Tufts Medical Center; Medical Director for Home Dialysis, Dialysis Clinics, Inc, Somerville, MA; Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-5539

Dialysis, home dialysis, medical treatment for kidney failure without dialysis, general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Lesley A.  Inker, MD, MS

Lesley A. Inker, MD, MS

Accepting New Patients

Title(s): Director, Kidney and Blood Pressure Center; Director, Kidney Function and Evaluation Center; Director, Quality Improvement; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Geriatric nephrology, pregnancy, HIV-associated kidney disease, kidney transplantation, kidney donor evaluation, medical treatment for kidney failure without dialysis, kidney function evaluation (GFR), general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Scott J. Gilbert, MD

Scott J. Gilbert, MD

Accepting New Patients

Title(s): Director, Fellowship Training Program; Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Kidney transplantation, systemic lupus erythematosus, dialysis, general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Research + Clinical Trials


The Dialysate Sodium Lowering Trial (DeSaLT)

This is a pilot randomized clinical triaql in which hypertensive hemodialysis patients will be randomized to a low dialysate sodium (na) of 135 mEq/L or a standard dialysate Na or 138 mEq/L.Patients will be randomized 2:! to the low arm. Dialysate Na will be lowered 1 meE1/L every 2 weeks, as tolerated. Tolerance will be assessed by symptoms, intradialytic hyotension (IDH) episodes (systolic BP <90 or intervention for symptoms of BP drop during dialysis), achievemenbt of dry weight. The trial will last for 6 to 12 monthws, for an individual, depending on when the entered the trial. The primary outcome is feasibility and safety of using the lower dialysate sodium which is assessed by symptoms during or immediately after dialysis, intradialytic hypotention episodes and the frequency of emergency room visits and hospitalizations. Several secondary outcomes will be measured including blood pressure prior to dialysis and at home, change in plasma Na over time, dry weight, post-dialysis weight, interdialystic weight change, symptoms of thirst and dry mouth, self reported dialysis recovery time, relative blood volume change during a single treatment (via 'Critline') and, in patients without an implanted electronic device, extracellular fluid volume (via bioimpedance).
More information about research and clinical trials