Multinodular Goiter

A toxic nodular goiter involves an enlarged thyroid gland that contains rounded growths called nodules. These nodules produce too much thyroid hormone. A multinodular goiter involves multiple nodules within the goiter but its cause is less clear.


Programs + Services


General Endocrine Clinic

The General Endocrine Clinic at Tufts Medical Center in Boston provides evaluation and treatment for patients with a wide range of endocrine disorders.
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Thyroid Disease Clinic

The Thyroid Disease Clinic at Tufts Medical Center in Boston provides comprehensive diagnostic services and treatment for hyperthyroidism, hypothyroidism and thyroid cancer.
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Doctors + Care Team

Anastassios G. Pittas, MD, MS

Anastassios G. Pittas, MD, MS

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Accepting New Patients

Virtual Appointments Available

Online Scheduling Available

Title(s): Division Chief and Fellowship Program Director; Co-Director, Diabetes and Lipid Center; Professor, Tufts University School of Medicine
Department(s): Medicine, Endocrinology, Diabetes and Metabolism
Appt. Phone: 617-636-5689
Fax #: 617-636-4719

• Efficient, patient-centered care delivery that balances in-person with virtual care and digital connectivity
• Prevention of diabetes
• Diabetes management and prevention of diabetes-related complications
• Diagnosis and management of hypoglycemia
• Vitamin D deficiency

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picture of Andrew S. Greenberg, MD

Andrew S. Greenberg, MD

Title(s): Endocrinologist; Dr. Robert and Veronica Atkins Professor in Metabolism and Nutrition, Tufts University School of Medicine
Department(s): Medicine, Clinical Nutrition, Endocrinology, Diabetes and Metabolism
Appt. Phone:
Fax #:

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Jacqueline T. Kung, MD

Jacqueline T. Kung, MD

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Accepting New Patients

LGBTQ+ Health

Virtual Appointments Available

Online Scheduling Available

Title(s): Director, Thyroid Disease Clinic; Endocrinologist; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Endocrinology, Diabetes and Metabolism
Appt. Phone: 617-636-5689
Fax #: 617-636-8187

Thyroid disease, neck ultrasound, thyroid nodules, thyroid cancer, thyroid fine needle aspiration biopsy

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Ronald M. Lechan, MD, PhD

Ronald M. Lechan, MD, PhD

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Accepting New Patients

Virtual Appointments Available

Online Scheduling Available

Title(s): Co-Director, Hypothalamic and Pituitary Disease Center; Professor, Tufts University School of Medicine
Department(s): Medicine, Endocrinology, Diabetes and Metabolism
Appt. Phone: 617-636-5689
Fax #: 617-636-4719

Hypothalamic disease, pituitary disease, disorders of the thyroid, adrenal disease, islet cell tumors

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Miriam O'Leary, MD, FACS

Miriam O'Leary, MD, FACS

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Accepting New Patients

Virtual Appointments Available

Title(s): Interim Chair, Department of Otolaryngology — Head and Neck Surgery; Otolaryngologist; Associate Professor, Tufts University School of Medicine
Department(s): Otolaryngology
Appt. Phone: 617-636-3030
Fax #: 617-636-1479

Head and neck cancer, management of thyroid cancer and hyperparathyroidism, head and neck reconstruction including microvascular techniques, management of radiation-related complications

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Richard O. Wein, MD, FACS

Richard O. Wein, MD, FACS

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Accepting New Patients

Virtual Appointments Available

Title(s): Chief, Division of Head and Neck Surgery; Associate Professor, Tufts University School of Medicine
Department(s): Otolaryngology
Appt. Phone: 617-636-8711
Fax #: 617-636-1479

Head and neck surgical oncology, head and neck reconstruction, management of salivary and thyroid disorders, management of radiation-related complications, maxillofacial trauma, sleep apnea and sleep endoscopy

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Research + Clinical Trials


Sample Collection for Clinical Performance Evaluation of Elecsys Anti-TPO II

The purpose of this study is to collect blood samples for the further development of the diagnostic test Elecsys® Anti TPO II (anti-thyroid peroxidase antibody). This updated test is to aid in the diagnosis of autoimmune thyroid diseases like Hashimoto thyroiditis or Graves’ disease. In blood of patients suffering from these diseases, antibodies like anti-TPO are generally elevated. In the This study, the patient's blood sample will be analyzed with the updated Elecsys® Anti-TPO II test. The anti TPO levels from blood of patients with Hashimoto thyroiditis or Graves’ disease will be compared with levels from blood of patients with non-autoimmune thyroid diseases (e.g. thyroid cancer) or autoimmune non-thyroid diseases (e.g. Type I diabetes mellitus). This comparison will help to understand how good the Anti-TPO test can aid in the diagnosis of autoimmune thyroid diseases.

Participation in this study will involve one visit and will last approximately 30 minutes. We expect approximately 660 people in the US will participate in the study in the US in accordance with applicable national laws and globally recognized principles. Participation in this study will involve one blood collection for research purposes.


More information about research and clinical trials