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Osteoarthritis

Osteoarthritis (OA) is the most common joint disorder, which is due to aging and wear and tear on a joint.

Programs + Services


Rheumatology

The Division of Rheumatology at Tufts Medical Center in Boston offers comprehensive evaluation, consultation and management of arthritis and rheumatic disease.
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Osteoarthritis Program

The Osteoarthritis Program at Tufts Medical Center in Boston is home to world-renowned experts in researching, diagnosing and treating OA.
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Center for Complementary and Integrative Medicine

The Center for Complementary and Integrative Medicine in the Division of Rheumatology at Tufts Medical Center works to use alternative therapies to help patients with arthritis and rheumatic diseases.
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Doctors + Care Team

Timothy E. McAlindon, MD, MPH

Timothy E. McAlindon, MD, MPH

Title(s): Chief, Division of Rheumatology; Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

Osteoarthritis, general rheumatology, lupus

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Janeth Yinh, MD

Janeth Yinh, MD

Title(s): Rheumatologist; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, musculoskeletal ultrasound

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Robert A. Kalish, MD

Robert A. Kalish, MD

Title(s): Director, Rheumatology Education; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, Lyme disease

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Senada Arabelovic, DO

Senada Arabelovic, DO

Title(s): Rheumatologist; Assistant Professor of Medicine, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, transitioning young adults with autoimmune diseases to the adult rheumatology clinic, pregnancy in rheumatologic disease

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Steven C. Vlad, MD, PhD

Steven C. Vlad, MD, PhD

Title(s): Rheumatologist; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

General rheumatology, spondyloarthopathies, psoriatic arthritis and anklylosing spondylitis

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William F. Harvey, MD, MSc, FACR

William F. Harvey, MD, MSc, FACR

Title(s): Rheumatologist; Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Rheumatology
Appt. Phone: 617-636-5990
Fax #: 617-636-2388

Osteoarthritis, general rheumatology, Musculoskeletal Ultrasound

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Research + Clinical Trials


A Cross-sectional Observational Study Evaluating the Effect of intra-Articular Steroids or Placebo Previously Injected in the target Knee Joint of Subjects on structural Progression of Knee Osteoarthritis.

The purpose of the study is to evaluate for long term changes in pain and function in knee osteoarthritis and also to ascertain differences in health care utilization among subjects who participated in the randomized controlled trial on effect of intra-articular steroids on structural progression of knee osteoarthritis (IACS)
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A Randomized, Double-Blind, Placebo-Controlled, Single Injection, 52-Week Study to Evaluate the Efficacy and Safety of an Intra-articular Injection of CNTX-4975-05 in Subjects with Chronic, Moderate-to severe Osteoarthritis Knee Pain

The study evaluates the analgesic efficacy on pain with walking of a one-time knee injection for patients with moderate to severe knee osteoarthritis. CNTX-4975-05 is the investigational drug that has not been approved by the FDA. The study drug is a long-acting, non-opioid analgesic drug candidate designed to provide pain relieve. Subjects will be randomly assigned to one of two groups: study drug group, or a placebo group.
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A Phase 3 Randomized, Double-Blind, Multi-Dose, Placebo and NSAID-Controlled Study to Evaluate the Efficacy and Safety of Fasinumab in Patients with Pain due to Osteoarthritis of the Knee or Hip

This study evaluates the efficacy and safety of fasinumab compared to placebo, diclofenac, and celecoxib (diclofenac and celecoxib are standard-of-care non-steroidal anti-inflammatory drugs, NSAIDs, used for moderate-to-severe pain due to OA). The study drug will be administered for up to 24 weeks in patients with OA of the knee or hip. Fasinumab aims to selectively block nerve growth factor (NGF), a protein that causes pain. Blocking NGF may reduce pain due to OA of the hip and knee. Fasinumab is being test and is not approved for use in pain management by the United States Food and Drug Administration (FDA).
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A prospective Study to Evaluate the Safety and Effectiveness of the Cartiva® Synthetic Cartilage Implant for CMC in the Treatment of First Carpometacarpal Joint Osteoarthritis as Compared to a Ligament Reconstruction Tendon Interposition (LRTI) Comparator

The purpose of this research study is to determine the safety and effectiveness of a new treatment for osteoarthritis of the first carpomeetacarpal joint (base of your thumb). The new treatment uses the Cartiva Synthetic Cartilage Implant (Cartiva implant) to replace damaged cartilage in your thumb joint. The most common treatment is called ligament reconstruction tendon interposition (LRTI), where the bone is surgically removed and the joint us stabilized using the surrounding tendons. 

You will need to have the following exam, tests, and procedures to find out if you can be in the study. The exam, tests, and procedures are part of your regular thumb arthritis care and may be done even if you do not join the study. If you have had some of these done recently, they may not need to be repeated. This will be up to your study doctor. 

After surgery you will need to come back for follow up visits. These follow up visits will happen at 2 weeks, 6 weeks, 3 months, 6 months, 1 year, and each year up to 5 years after your hand surgery. The procedures performed during these visits are part of your regular thumb arthritis care. 

 


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200 Years of Caring for the Community

Tufts Medical Center has been taking care of Boston and the surrounding community for more than 200 years.

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