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Pulmonary Hypertension

Pulmonary hypertension is abnormally high blood pressure in the arteries of the lungs. It makes the right side of the heart work harder than normal.

Doctors + Care Team

Nicholas S. Hill, MD

Nicholas S. Hill, MD

Accepting New Patients

Title(s): Chief, Pulmonary, Critical Care and Sleep Division; Professor, Tufts University School of Medicine
Department(s): Medicine, Pulmonary, Critical Care and Sleep Medicine
Appt. Phone: 617-636-6377
Fax #: 617-636-1649

Pulmonary hypertension, mechanical ventilation, noninvasive ventilation, general pulmonology

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Ambalavanan Arunachalam, MD

Ambalavanan Arunachalam, MD

Accepting New Patients

Title(s): Pulmonary and Critical Care Attending Physician
Department(s): Medicine, Pulmonary, Critical Care and Sleep Medicine
Appt. Phone: 617-636-6377
Fax #: 866-612-2514

Pulmonary and critical care, pulmonary hypertension

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Ioana R. Preston, MD

Ioana R. Preston, MD

Accepting New Patients

Title(s): Pulmonary Function Lab Director; Director, Pulmonary Hypertension Center; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Pulmonary, Critical Care and Sleep Medicine
Appt. Phone: 617-636-6377
Fax #: 617-636-1649

Pulmonary hypertension, critical care medicine, general pulmonology

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Kari E. Roberts, MD

Kari E. Roberts, MD

Accepting New Patients

Title(s): Director, Bronchoscopy Service; Associate Chief Medical Officer, Graduate Medical Education; Designated Institutional Official, Graduate Medical Education; Associate Program Director, Internal Medicine Residency; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Pulmonary, Critical Care and Sleep Medicine
Appt. Phone: 617-636-6377
Fax #: 617-636-1649

General pulmonology, pulmonary hypertension, critical care medicine

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Sucharita R. Kher, MD

Sucharita R. Kher, MD

Accepting New Patients

Title(s): Director, Outpatient Pulmonary Clinic; Pulmonary Attending Physician; Instructor, Tufts University School of Medicine
Department(s): Medicine, Pulmonary, Critical Care and Sleep Medicine
Appt. Phone: 617-636-6377
Fax #: 617-636-1649

Pulmonary diseases, critical care medicine

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Research + Clinical Trials


206246 : An Open-label, Dose-escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of GSK2586881 in Participants with Pulmonary Arterial Hypertension

The purpose of this study is to test the safety of different doses of the study drug (GSK2586881) to find out if it causes any changes to the pressures inside the heart and lungs of patients who have Pulmonary Arterial Hypertension (PAH).
More information about research and clinical trials


A Dose-Ranging Study of the Efficacy and Safety of Bardoxolone Methyl in Patients With Pulmonary Arterial Hypertension

This study assesses the safety and efficacy of bardoxolone methyl relative to placebo in patients with pulmonary arterial hypertension to determine the recommended dose range and evaluate the change from baseline in 6-minute walk distance (6MWD) following 16 weeks of study participation.

This is a two-part study.

Part 1: Part 1 of the study will include both dose-escalation and expansion cohorts.

Part 2 (extension period): All patients from Part 1 who complete the 16-week treatment period as planned will be eligible to continue directly into the extension period to evaluate the intermediate and long-term safety and efficacy of bardoxolone methyl.


More information about research and clinical trials

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