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Seizures

A seizure is the physical findings or changes in behavior that occur after an episode of abnormal electrical activity in the brain. The term "seizure" is often used interchangeably with "convulsion." Convulsions are when a person's body shakes rapidly and uncontrollably. During convulsions, the person's muscles contract and relax repeatedly. There are many different types of seizures. Some have mild symptoms and no body shaking.

Doctors + Care Team

James Kryzanski, MD

James Kryzanski, MD

Title(s): Chief, Division of Epilepsy Surgery; Co-Chief, Division of Spinal Surgery; Assistant Professor, Tufts University School of Medicine
Department(s): Neurosurgery
Appt. Phone: 617-636-8585
Fax #: 617-636-7587

Epilepsy neurosurgery, skull base surgery, pituitary surgery, neurovascular surgery, minimally invasive spine surgery, neurosurgical disorders in patients with achondroplasia, neurosurgical disorders in patients with Down syndrome

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Joel Oster, MD

Joel Oster, MD

Title(s): Neurologist
Department(s): Neurology
Appt. Phone: 617-636-5848
Fax #: 617-636-8199

Epilepsy, intractable epilepsy, detection of difficult to find possible lesions causing epilepsy, structural and metabolic brain imaging, clinical drug trials for seizure disorders, general neurology, sleep disorders, neurologic/epilepsy intensive monitoring, intraoperative neurophysiologic monitoring

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Ju Tang, MD, PhD

Ju Tang, MD, PhD

Title(s): Director, Pediatric Epilepsy Program and Pediatric EEG Laboratory; Pediatric Neurologist; Epileptologist; Assistant Professor, Tufts University School of Medicine
Department(s): Pediatrics, Pediatric Neurology
Appt. Phone: 617-636-8100
Fax #: 617-636-8375

Epilepsy, pediatric neurology

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Research + Clinical Trials


A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of SAGE-547 Injection in the Treatment of Subjects with Super-Refractory Status Epilepticus

The purpose of the study is to find out if SAGE-547 has any effect on continuous seizures and if it is safe to use in patients in super-refractory status epilepticus (SRSE). SAGE-547 Injection (SAGE-547) is an investigational drug being studied in patients with continuous seizures (seizures that have little or no break between them) that do not respond to seizure medications.
More information about research and clinical trials

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