Advanced Colorectal Cancers

The Advanced Colorectal Cancer Program at Tufts Medical Center in Boston uses a team approach to aid patients with advanced cancer that is metastatic or has spread locally. Our team offers an array of cutting-edge treatment options that offer hope for prolonged survival and improved quality of life. 

We use a Colorectal Oncology Tumor Board to discuss each patient’s case and determine the best possible treatment plan. The typical treatment plans for colorectal cancer include a number of options depending on your diagnosis. At Tufts MC, we offer:


  • Chemotherapy
  • Radiation therapy
  • Y-90 (SIR-Spheres) - learn more by watching the video below
  • Medication therapy – this may include anti-angiogenesis therapy and Epidermal Growth Factor Receptor (EGFR) Inhibitors
  • Clinical Trials


  • Minimally Invasive Surgery
  • Enterostomal therapy
  • Intra-operative brachytherapy (radiation)
  • Wide visceral excision and reconstruction
  • Pelvic exenteration
  • Hyperthermic intraperitoneal chemotherapy (HIPEC) for widespread intra-abdominal disease
Y-90 (SIR Spheres) Procedure