Cancer Center

Hematologic Malignancies Program

Personalized care for patients with blood cancer

Hematologic malignancies of the blood, bone marrow or lymph nodes include a wide array of cancers, each requiring different therapies. That's why making the right diagnosis is so critical to your care.

In the Hematologic Malignancies Program at Tufts Medical Center in Boston, we use the latest diagnostic techniques to pinpoint your cancer type and provide you with the most effective treatment from the start. Once we have a precise diagnosis, our team works with you and with Tufts MC specialists from Surgeons to Radiation Oncologists to Critical Care Specialists to develop and execute a comprehensive treatment plan that's personalized to meet your needs.

Tufts MC has been a leader in the field of hematology since the early 1950s, when two of our physician researchers, Robert Schwartz, MD and William Damashek, MD, helped found the modern age of hematologic care.  Together they discovered that medications could be used to suppress the immune system, innovation which enabled the field of organ transplantation.  Their work led to the first bone marrow transplants performed in Boston in 1959, among the first blood transplants performed in the world.
Today, our experienced team of doctors and nurses continues this legacy of innovation with groundbreaking research and compassionate care for all hematologic malignancies. We are fortunate to have National experts in all hematologic malignancies, including:
  • Acute and chronic leukemias
  • Hodgkin's and non-Hodgkin's lymphoma
  • Myeloma/amyloidosis (cancers of plasma cells)
  • Myelodysplastic syndromes (blood disorders that often progress to leukemia)
  • Myeloprofierative disorders (a term coined by Dr. Dameshek himself to describe progressive overgrowths of blood components)

Which blood cancer treatment is right for me?

If you're living with leukemia, lymphoma or myeloma, the treatment options can seem overwhelming. Our doctors work exclusively to study and treat blood cancers and are expert communicators and will ensure you understand your diagnosis and treatment options. Together, we will develop a plan of care that right for your cancer type, health history and lifestyle.

We use precise histologic, molecular and genetic testing to pinpoint your diagnosis and develop an effective, personalized treatment plan.

Targeted Therapy

Armed with the results of your diagnostic testing, our doctors can administer the latest drugs, designed to target the growth of your specific cancer type.  Targeted therapies are revolutionizing the care of blood cancers once again.  Our physicians provide access to the latest approved and experimental therapies for your cancer.

Chemotherapy & Radiation Therapy

Chemotherapy, radiation therapy or a combination of both these therapies remain the mainstay of treatment for the blood cancers.  The combined experience of our doctors, pharmacists and nurses will ensure that your care is delivered with the utmost precision in a setting of uncompromized personal, compassionate care.

Immunotherapy

Immunotherapy engages your body's own immune system to fight your cancer.  In the last decade, combinations of chemotherapy and immunotherapy have produced unparalleled treatment success and have increased the likelihood of cure for many blood cancer types.

Stem Cell Transplantation

If you require a bone marrow transplant, you won’t need to meet another doctor - your doctor is already part of the team from the Tufts MC Bone Marrow and Stem Cell Transplant Program. Having the same doctor from start to finish ensures exceptional continuity, precise communication and personal attention to your care. Since performing the first bone marrow transplant in Boston, we've helped more than 1,300 patients find new hope with this life-saving procedure.

Clinical Trials

Our doctors are constantly striving to improve care for our patients.  Our clinical trials program ensures your access to the most innovative and promising drugs and procedures from the pharmaceutical industry and our own research laboratories across the Tufts campus.  Our doctors are leaders in the development of new treatments in cancer care and transplantation.

Our doctors are active collaborators in cooperative trial groups that work together on national and international levels to set new standards of care for today and innovate the next generation of treatments for tomorrow. 

Meet your blood cancer team

Andreas Klein, MD leads the Hematologic Malignancies Program. Dr. Klein has a long-standing interest in lymphoma, multiple myeloma and especially stem cell/bone marrow transplantation. Dr. Klein is also the Director of the Institutional Review Board charged with assuring the rights and welfare of research participants across the Tufts Health Sciences campus. 

Along with Dr. Klein, our team includes specialists who hold leadership roles in the American Society of Hematology and the American Society of Clinical Oncology. Our doctors have been recognized consistently for their excellent care; in fact, many have been designated Top Doctors by U.S. News and World Report.

Yun Choi, MD

Yun Choi, MD

Accepting New Patients

Title(s): Hematologist: Assistant Professor, Tufts University School of Medicine
Department(s): Medicine, Hematology/Oncology
Appt. Phone: 617-636-6227
Fax #: 617-636-8538

Lymphoid malignancies, including non-Hodgkin lymphoma, Hodgkin lymphoma, myeloma and lymphocytic leukemias, CAR T-cell therapy

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Raymond L. Comenzo, MD

Raymond L. Comenzo, MD

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Accepting New Patients

Virtual Appointments Available

Title(s): Director, Transfusion Services; Director, John C. Davis Myeloma and Amyloid Program; Professor, Tufts University School of Medicine
Department(s): Medicine, Pathology and Laboratory Medicine, Hematology/Oncology
Appt. Phone: 617-636-6454
Fax #: 617-636-3175

Myeloma, amyloidosis, stem cell transplant, transfusion medicine

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Andreas K. Klein, MD

Andreas K. Klein, MD

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Accepting New Patients

Virtual Appointments Available

Title(s): Associate Chief, Division of Hematology Oncology; Director, Hematologic Malignancies Program; Director, Bone Marrow and Hematopoietic Cell Transplant Program; Regulatory Affairs Director, CTSI; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Hematology/Oncology
Appt. Phone: 617-636-6227
Fax #: 617-636-8538

Lymphoma, myeloma, bone marrow transplantation (BMT), immune reconstitution after BMT

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Raphael A. Lizcano, MD

Raphael A. Lizcano, MD

Accepting New Patients

Title(s): Hematologist/Oncologist
Department(s): Medicine, Hematology/Oncology
Appt. Phone: 617-636-6227
Fax #: 617-636-8538

myeloid malignancies including myeloid leukemias, myelodysplastic syndrome, myeloproliferative neoplasms, allogeneic transplant

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Monika Pilichowska, MD, PhD

Monika Pilichowska, MD, PhD

Title(s): Director, Clinical Hematology and Hematopathology; Director, Hematopathology Fellowship Program; Associate Professor, Tufts University School of Medicine
Department(s): Pathology and Laboratory Medicine
Appt. Phone: 617-636-7216
Fax #: 617-636-7128

Hematology and hematopathology, flow cytometry, surgical pathology and cytology, renal pathology (medical renal disease)

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Zheng

Zheng "Frank" Zhou, MD, PhD

Accepting New Patients

Title(s): Hematologist, Stem Cell Transplant Physician, Associate Director, Adult Stem Cell Transplantation and Cellular Therapy
Department(s): Medicine, Hematology Oncology, Stem Cell Transplantation and Cellular Therapy
Appt. Phone: 617-636-6227
Fax #: 617-636-8538

Stem Cell Transplantation, Leukemias, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Hematological Malignancies

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We understand that living with cancer is difficult for you and your family, and we try to help in every way we can. Your care team takes the time to get to know you, answer your questions and address your concerns. In addition, a social worker is always available to connect you and your family with the many support services available at Tufts MC and throughout the community.

We strive to make your care as convenient and stress-free as possible. For example, our pharmacy is located on the same floor as our infusion center. Patients receiving outpatient treatments also have access to the Neely House at Tufts MC, a bed and breakfast-style home-away-from-home for you and your family.

We appreciate the importance of maintaining close relationships with referring physicians and will communicate with you throughout your patient's course of treatment.