Ear, Nose + Throat (ENT) - Head + Neck Surgery

Otolaryngology Research Center


Advancing Endoscopic + Minimally-Invasive Otolaryngologic Surgery through Basic + Applied Research

The Otolaryngology Research Center at Tufts Medical Center is dedicated to basic and applied research in advanced endoscopic and minimally-invasive otolaryngologic surgery. It provides the opportunity to develop and test instruments, undertake laboratory and animal research, and provides training in new techniques in both conventional and laser surgery.

The entire Department of Otolaryngology-Head and Neck Surgery participates in research activities in otolaryngology and allied specialties. These efforts have produced numerous innovations in the diagnostic and surgical applications of lasers. These have lead to improvements in patient care by providing surgeons with advanced knowledge of laser-tissue interaction and the optimal application of technology towards more effective and safer procedures.

The Otolaryngology Research Center is also utilized for the education of residents in the training program. Each resident completes a three month research block in their third year of training (PGY-3). Many residents have participated in research projects within the Otolaryngology Research Center and have presented and/or published their research.

Principal Investigator + Research Team

Elie E. Rebeiz, MD - Director
Arnold S. Lee, MD
Richard O. Wein, MD
Mark A. Vecchiotti, MD
Miriam O'Leary, MD
Andrew Scott, MD
Jonathon Sillman, MD

Current Projects

Sentinel Lymph Node Biopsy in Head & Neck Cutaneous Squamous Cell Carcinoma.  Aldahlawi M, Chan C, Lee A, O'Leary M.

We are a site for ECOG 1308 "A Phase II Trial of Induction Chemotherapy Followed by Cetuximab (Erbitux) with Low Dose vs. Standard Dose IMRT in Patients with HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx".  Tufts Medical Center Principal Investigator - M. O'Leary

We are a site for Novartis study "Randomized Phase II Trial of Everolimus versus Placebo as Adjuvant Therapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck." Tufts Medical Center Principal Investigator - M. O'Leary

Oral and nasopharyngeal cytologic diagnosis by infrared micro-spectroscopy in collaboration with Northeastern University Comparison of oral cancer screening techniques with surgical biopsy results (IRB#9169) - R. Wein

Recent Presentations

Parapharyngeal tumors: 2nd Annual Cherry Blossom Conference Otolaryngology Update – April 2011: Elie Rebeiz, M.D.

Isolated sphenoid sinus inverted papilloma diagnosis and management options: Rhinology Society meeting – April 2011:  Jonathan Bass, TUSM M11, Anish Parekh, M.D., Elie Rebeiz, M.D.

Overview & Epidemiology of Head & Neck Cancer: Miriam O'Leary, MD. Comparative Oncology Symposium and Poster Session.  Cummings School of Veterinary Medicine at Tufts University.  May 12, 2011

Head & Neck Program In-Development - Richard O. Wein, MD.  Comparative Oncology Symposium and Poster Session.  Cummings School of Veterinary Medicine at Tufts University.  May 12, 2011

6th Annual Saudi General Surgical Society Scientific Meeting in Jeddah, Saudi Arabia Richard Wein presented the following:

  • Management of papillary microcarcinoma
  • Thyroidectomy: Technical considerations
  • Anaplastic thyroid carcinoma
  • Management of lateral neck disease
  • Medullary thyroid carcinoma

Liposarcoma of the Larynx Presenting with Stridor: A Rare Tumor: Herman P. Lam, BS,; Arnold S. Lee, MD.; Elie E. Rebeiz, MD.  Triological Society– January 2011

Recent Published Papers

Hoppo T, Sanz A, Nason KS, Carroll TL, et al. How Much Pharyngeal Exposure is "Normal?" Normative Data for Laryngopharyngeal Reflux Events Using Hypopharyngeal Multichannel Intraluminal Impedance (HMII).  Journal of Gastrointestinal surgery 2011.  Accepted for publication

Carroll TL, Wu YE, McRay M and Gherson S.  Frame by Frame Analysis of Glottic Insufficiency Using Laryngovideostroboscopy.  Journal of Voice 2011.  Accepted for publication.

Carroll TL and Rosen CA. Long term results of Calcium Hydroxylapatite for Vocal Fold Augmentation.  Laryngoscope 2011.  ePub  ahead of print.

Use of intraoperative laryngeal electromyography to evaluate stridor in children with arthrogryposis.  Scott AR, Kudak BA, Skinner S, Sidman JD.  Ann Otol Rhinol Laryngol. 2011 Mar;120(3):150-4.

Mandibular distraction osteogenesis in infants younger than 3 months.  Scott AR, Tibesar RJ, Lander TA, Sampson DE, Sidman JD.  Arch Facial Plast Surg. 2011 May-Jun;13(3):173-9. Epub 2011 Jan 17.

Microglossia in a newborn: a case report and review of the literature.  Voigt S, Park A, Vecchiotti MA.  Laryngoscope. 2010;120 Suppl 4:S200.

Wein RO, Weber RS. Anaplastic thyroid carcinoma: Palliation or Treatment. Current Opinion in Otolaryngology-Head & Neck Surg 2011 Apr;19(2):113-8.

Aljumaily RM, Nystrom JS, Wein RO. Neoadjuvant chemotherapy in the setting of locally advanced olfactory neuroblastoma with intracranial extension. Rare Tumors 2011 Mar 30;3(1):e1.

Miriam O'Leary, MD is a boston doctor at Tufts Medical Center.

Early detection tips for head and neck cancers

Miriam O'Leary, MD identifies the causes, symptoms and importance of early detection steps.

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