Services + Approach to Care

We use the most recent medical information to create an individualized plan of care for our patients with glomerular diseases. At Tufts Medical Center, our goal is to give each patient a lifetime of individualized care. We help patients understand what is known and what is not known about their disease and treatments to make the best care decisions with them.

Services

Diagnosis (kidney biopsy, blood testing, imaging, genetic testing)

If the type of kidney disease has not been determined or is in question, we can help determine the cause of your kidney disease by doing specializing testing of the blood and urine, obtaining imaging of your kidneys, performing a biopsy to obtain a sample of kidney tissue, or by arranging for genetic testing for inherited kidney diseases.

Specific services offered:

  1. Kidney biopsy: It is often necessary to obtain a small sample of kidney tissue and cells to diagnosis glomerular disease.  We perform all kidney biopsies at Tufts using ultrasound or CAT scan guidance, so as to ensure we sample an adequate amount of the kidney and minimize the risks of bleeding.

  2. Blood (Serological) testing: Blood tests for glomerular disease are increasingly used to help diagnosis specific types of glomerular disease. The follow are examples of some tests we may recommend: primary membranous (anti-PLA2R antibody and THSD7A antibody), monoclonal gammopathy of renal significance (identification of monoclonal proteins), complement associated disorders (genetic and functional screening), thrombotic thrombocytopenic purpura (rapid turnaround ADAMTS13)

  3. Imaging: In certain cases, it may be recommended that you get pictures taken of your kidneys (examples include kidney ultrasounds, CAT scan, or MRI scans).

  4. Genetic testing: Some kidney disease have a genetic component; identification of a genetic mutation can help us determine if certain treatments will be benefit you or not.

Second opinion 

We can review your prior workup of kidney disease and provide a second opinion of your existing diagnosis and/or treatment plan. We will review your medical records paying close attention to laboratory tests, imaging, and any prior kidney biopsy results. We can request the stored kidney tissue (if available) from the center which performed the biopsy and have our pathologists directly review the kidney biopsy.

Once we have carefully reviewed all your information, we will meet with you to discuss our findings and any suggestions we have for additional testing or treatments.
some kidney disease have a genetic component; identification of a genetic mutation can help us determine if certain treatments will be benefit you or not.

Treatment

We can provide the appropriate treatment for your kidney disease. Treatments may include oral medications or intravenous infusions including medicines which suppress the immune system (a common underlying cause of many glomerular diseases).