Nephrology

Center for Polycystic Kidney Disease

Helping you take control of your polycystic kidney disease

Polycystic kidney disease (PKD) is a complex condition that can impact your health in many ways. To manage PKD properly, you need more than a specialist; you need a team of doctors working together to give you the individualized care it takes to manage your symptoms and take control of your health.

At the Center for Polycystic Kidney Disease at Tufts Medical Center, our goal is to give patients a lifetime of individualized care. Our team treats patients with both autosomal dominant polycystic kidney disease (ADPKD) and the less common autosomal recessive polycystic kidney disease (ARPKD). 

Most importantly, we understand what it's like to live with PKD. We're here to address all of your needs, from pain management and genetic counseling to providing access to promising new drug therapies.

We work closely with our colleagues in the Nephrology Division to provide seamless care for all aspects of your condition. In addition, we collaborate with specialists throughout Tufts MC to evaluate and manage complications such as kidney stones, brain aneurysms and liver cysts. Multidisciplinary consultations are provided in collaboration with

Our suite of services includes: 

  • Advice and counseling on all aspects of cystic kidney disease
  • Comprehensive, multidisciplinary care for all stages of chronic kidney disease
  • Surgical treatments (e.g. laparoscopic cyst reduction)
  • Pain-management therapies (e.g. video thorascopic splanchnicectomy, or VSPL)
  • Image guided cyst aspiration and ablation
  • Dialysis services, including access surgery
  • Kidney transplantation and donor-matching services
  • Genetic screening, counseling and family planning
  • Nutritional and other lifestyle counseling
  • Access to clinical trials to slow progression in ADPKD. 

Drs. Perrone, Miskulin, and Gordon participate in clinical trials for patients with ADPKD including tesevatinib (Kadmon), metformin (TAME), bardoxolone (FALCON, Reata), and venglustat (STAGED-PKD, Sanofi). 

Unique support for new patients

If you've been newly diagnosed with PKD, you have a lot to think about. Even if PKD runs in your family, the diagnosis can be concerning. That's why we set aside time each week just to meet with new patients.

During your first appointment at the Center, we sit down with you to discuss your personal health history and answer your questions. Then we work with you to develop a treatment plan that fits your unique needs.

Meet our Director, Dr. Ronald Perrone

Led by Ronald Perrone, MD, our team of nephrologists and other specialists provide the best — and most advanced — PKD care. Throughout Dr. Perrone's career, he has consistently been recognized for his excellence in clinical care and research. U.S. News & World Report has designated him a "Top Doctor" and ranked him among the top 1% of the nation's nephrologists.
Dr. Perrone and his team are at the forefront of PKD research, and we bring the latest treatments right to you. Our physicians and patients participate in the nation's most advanced clinical trials including tesevatinib (Kadmon), metformin (TAME), bardoxolone (FALCON, Reata), and venglustat (STAGED-PKD, Sanofi).. For example, Tufts MC is one of only seven centers in the country to be part of the groundbreaking HALT-PKD study, which aims to slow the progression of the disease

Craig E. Gordon, MD, MS

Craig E. Gordon, MD, MS

Accepting New Patients

Title(s): Nephrologist; Visiting Associate Professor of Medicine, TUSM
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #:

Hepatitis C virus in chronic kidney disease, Thrombotic microangiopathy, polycystic kidney disease (PKD), glomerular disease, kidney transplantation, chronic kidney disease

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Dana C. Miskulin, MD, MS

Dana C. Miskulin, MD, MS

Accepting New Patients

Title(s): Nephrologist; Associate Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Polycystic kidney disease (PKD), dialysis, home dialysis, general nephrology, chronic kidney disease (CKD), diabetic kidney disease, glomerular disease, vasculitis, hypertension, cardiovascular disease in patients with kidney disease, acute kidney disease, acute kidney injury and kidney stones

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Ronald D. Perrone, MD

Ronald D. Perrone, MD

Accepting New Patients

Title(s): Scientific Director, Clinical and Translational Research Center; Professor, Tufts University School of Medicine
Department(s): Medicine, Nephrology, Clinical and Translational Research Center (CTRC)
Appt. Phone: 617-636-5866
Fax #: 617-636-2369

Polycystic kidney disease (PKD)

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Ronald Perrone, MD on tuftsmedcalcenter.tv video.

Polycystic Kidney Disease

Watch Ronald Perrone, MD discuss the symptoms and treatment options for this genetic disease

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